An interventional study of ESP block in Surgery and Thoracic, sponsored by Andrea Saporito. Completed at 1 site in Switzerland. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-02-28.
Sponsored by Andrea Saporito · Not applicable, Interventional, and Treatment
The aim of the study is to compare two different locoregional techniques in VATS.
There are clear clinical and logistic reasons for pursuing the best possible post-operative pain management avoiding the negative side effects of opioid treatment; in order to garantee an enhanced recovery after surgery. A short hospital stay is fundamental to reduce patient morbidity and costs. Regional anesthetic nerve blocks are an ideal option to achieve this goal.
Paravertebral block serves as an ideal approach for thoracic and abdominal surgery through delivering segmental anesthesia of operative sites. Thoracic paravertebral block has superior analgesia as well as fewer complications than systemic opioids. It has been successfully applied in sternotomy, breast surgery, abdominoplasty, and laparoscopic cholecystectomy. ESP block is a recently described technique, with promising results in different scenarios. It probabily has a better risk profile than PVB, for its lower possibility of accidental pleural puncture and reabsorption of local anesthtetic than PVB one
Andrea Saporito is the lead sponsor of 4 studies on the registry; 3 are open to participants now.
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Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
ESP block will be performed with local anesthetic under US guide; instead TPV block with physiological solution
Procedure: ESP block
ESP block will be performed with physiological solution under US guide; instead TPV block with local anesthetic
Procedure: ESP block
US guided ESP infiltration (saline solution vs Ropivacaine 0.375% according to randomization): unilateral injection of 0,4 ml kg -1 (ideal weight)2 under US guidance between the deep fascia of erector spinae muscle and the two transverse processes at the level of the 5th thoracic vertebrae. Duration approximately 10-15 minutes
cumulative dose of opioids at 24 and 48 h
by using a PCA we will see how many times the patient asked for analgesia
Time frame: 48 hours
Pain scores at 4h, 8h, 24h, 48h via numeric rating scale (NRS) at rest and during cough
we will test pain score in several moment by asking the NRS scale at rest and during cough
Time frame: 48 hours
Hypotension
we will compare the systolic pressure before anesthesia and after the block have been performed
Time frame: 48 hours
Cardio-pulmonary complications
we will check if any cardio-pulmonary complication is present after surgery during the hospital stay
Time frame: 48 hours
Procedure time and complications
we will observe the time necessary to perform the block and the complications after it
Time frame: 48 hours
Need for anti-nausea medication (dosage, doses and time points)
We will observe if the patient need any type of anti-nausea medication
Time frame: 48 hours
Episodes of vomiting
We will observe if any episode of vomiting is present
Time frame: 48 hours
Episodes of urinary retention
We will observe if any episode of urinary retention is present
Time frame: 48 hours
Length of hospital stay
We will observe how long the hospital stay is
Time frame: 48 hours
Need for epidural catheter
We will observe if the patient needs for an epidural catheter
Time frame: 48 hours
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Feb 2025. You cannot join it, but the record below documents what was studied.
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Andrea Saporito