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CompletedNCT05783752Updated Jul 14, 2025

Short, Simple, Exercise to Improve Circadian Dependent Postprandial Glycemic Responses

An interventional study of Stair Stepping and No exercise control in Postprandial Glycemic Response, Postprandial Hyperglycemia and Postprandial Insulin, sponsored by San Diego State University. Completed at 1 site in United States. Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-07-14.

Sponsored by San Diego State University · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
35
Allocation
Randomized
Ages
18 Years to 65 Years
Sex
All
01

Study summary

The goal of this clinical trial is to test whether one minute of stair stepping at a comfortable pace can reduce blood sugar after meals. The main objectives of the study are:

Compare continuously measured post-meal glucose after stair-stepping to control condition Compare continuously measured post-meal glucose after stair-stepping between meals Assess interaction between condition and meal to determine if the effect of stair-stepping on post-meal glucose depends on meal

Participants will be in the study for 10 days and will be asked to:

Wear a continuous glucose monitor over the course of the study Perform either one minute of comfortable pace stair stepping 15 min after each meal OR no exercise 1 hour after eating a meal on alternating days Perform a dietary recall every two days Perform no exercise within one hour after each meal on any day during the study Consume no calories within one hour after each meal during the study

Read the detailed description

After being informed about the study and potential risks, all participants giving written informed consent will undergo a screening to determine eligibility for study entry. At day 1, patients who meet the eligibility requirements will be randomly assigned to Arm 1(stair stepping day followed by no exercise day sequence) or Arm 2(no exercise day followed by stair stepping day sequence). At this time participants will also be familiarized with the continuous glucose (i.e., blood sugar) monitor they will wear for ten days, be instructed how to fill out a food log every day and determine a comfortable stair stepping pace. On day 10 participants will return to the lab for sensor removal and transmitter return.

02

Conditions studied

  • Postprandial Glycemic Response
  • Postprandial Hyperglycemia
  • Postprandial Insulin

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03

In context

Hyperglycemia

699 studies on the registry are indexed under Hyperglycemia; 105 are open to participants now.

This study's enrollment of 35 is below the median of 46 across 521 interventional studies indexed under Hyperglycemia.

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Lead sponsor

San Diego State University is the lead sponsor of 145 studies on the registry; 41 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • between 18 and 65 years
  • able to climb and descend stairs
  • access to stairs

Exclusion criteria

Exclusion Criteria:

  • glycemic medications that vary in dosage
  • dosage from meal to meal or day to day (eg insulin titrated to meal size or carbohydrate content)
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Crossover assignment
Masking
Single (Outcomes assessor)
Enrollment
35 participants (actual)

Study arms

  • Experimental
    Stair-Stepping then Control

    Participants start with stair-stepping 15 minutes after meals on day 1 followed by no exercise on day 2. Sequence continues throughout the 10 days.

    Behavioral: Stair Stepping · Behavioral: No exercise control

  • Experimental
    Control then Stair-Stepping

    Participants start with no exercise on day 1 followed by stair-stepping 15 minutes after meals on day 2. Sequence continues throughout the 10 days.

    Behavioral: Stair Stepping · Behavioral: No exercise control

Interventions

  • BehavioralStair Stepping

    1 minute of stair-stepping (30 seconds up, 30 seconds down) at a self-selected pace identified on day 0 starting 15 minutes after each meal

  • BehavioralNo exercise control

    Participants avoid exercise within 1 hour of eating a meal

06

What researchers measure

Primary outcomes

  1. Postprandial Blood Glucose

    mg/dL

    Time frame: continuous measure from meal consumption up to 1 hour post meal

07

Study locations

1 site
  • San Diego State University
    San Diego, California 92182, United States
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 14, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05783752
Lead sponsor
San Diego State University
Responsible party
Sponsor
First posted
Mar 24, 2023
Start date
Feb 20, 2023
Primary completion
Aug 7, 2023
Completion
Aug 14, 2023
Last update
Jul 14, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2025. You cannot join it, but the record below documents what was studied.

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