An observational study in HIV Infections, sponsored by Fondazione Policlinico Universitario Agostino Gemelli IRCCS. Status unknown at 1 site in Italy. Per ClinicalTrials.gov, last updated 2023-03-02.
Sponsored by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Observational
The primary goal of this observational study is to evaluate prospective memory in HIV+ patients compared to healthy subjects. The secondary goal is to examine the relationship between prospective memory and Hot Cognition (mechanical cognitive abilities) and Cold Cognition (cognitive abilities supported by emotion and social perception). The main questions it aims to answer are:
4,258 studies on the registry are indexed under HIV Infections; 240 are open to participants now.
This study's planned enrollment of 100 is below the median of 200 across 713 observational studies indexed under HIV Infections.
Browse HIV Infections studies →Fondazione Policlinico Universitario Agostino Gemelli IRCCS is the lead sponsor of 920 studies on the registry; 529 are open to participants now.
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We expect the population with HIV and the healthy population compared by age (between 40 and 60 years old for the majority) and schooling (majority high school graduates). We expect a virologically suppressed HIV population with good adherence to antiretroviral therapy and deficits in prospective memory compared with the healthy population.
Inclusion Criteria HIV+:
Exclusion Criteria HIV+:
Inclusion Criteria HIV- :
Exclusion Criteria HIV+ :
Both male and female subjects, over 18 years of age, on antiretroviral therapy, native speakers of Italian
Other: Neuropsychological testing
Both male and female subjects, over the age of 18 years, no neurological or psychiatric conditions that would alter test performance, native speakers of Italian
Other: Neuropsychological testing
During the session the patient will be administered the Memory for Intentions Screening Test (MIST; Raskin et al., 2010) with the purpose of investigating prospective memory ability. Then during the same meeting the following tests will be offered to the patient: Montreal Cognitive Assessment (MOCA; Nasreddine. Translation Pirani et al 2006) investigating global cognitive performance; - Interpersonal Reactivity Index (IRI; Davis, 1980;1983- Italian version edited by Bonino et al, 1998) with the purpose of assessing cognitive and affective empathy (Hot cognition); Modified Five Point Test (Ruffi et al 1987) aimed at assessing figurative fluency (Cold cognition).
Prospective memory in HIV+ patients and healthy subjects
Prospective memory will be assessed through the following test: Memory for Intentions Screening Test (MIST).
Time frame: 1 year
Influence of global cognitive performance on prospective memory
Montreal Cognitive Assessment (MOCA) investigating global cognitive performance.
Time frame: 1 year
Influence of hot cognition on perspective memory
Interpersonal Reactivity Index (IRI) with the purpose of assessing cognitive and affective empathy (Hot cognition).
Time frame: 1 year
Influence of cold cognition on perspective memory
Modified Five Point Test aimed at assessing figurative fluency (Cold cognition).
Time frame: 1 year
Plan to share: No
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This study is status unknown, as verified in Jan 2023. You cannot join it, but the record below documents what was studied.
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Fondazione Policlinico Universitario Agostino Gemelli IRCCS