An interventional study of Capsules with B vitamins & taurine and Microcrystalline cellulose placebo in Healthy, sponsored by Société des Produits Nestlé (SPN). Completed at 1 site in Philippines. Open to participants aged 25 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-05-15.
Sponsored by Société des Produits Nestlé (SPN) · Not applicable, Interventional, and Basic science
To evaluate the efficacy of the intervention in improving Motivation.
To evaluate the efficacy of the intervention in improving Fatigue, Motivation/Vigor, Focus/Sustained Attention and blood levels of B vitamins and taurine.
Société des Produits Nestlé (SPN) is the lead sponsor of 314 studies on the registry; 16 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
IP will be administered orally once daily in capsule form, ideally between conventional mealtimes (i.e., breakfast, lunch, supper).
Dietary Supplement: Capsules with B vitamins & taurine
Placebo will be administered orally once daily in identical capsule form as the IP, ideally between conventional mealtimes (i.e., breakfast, lunch, supper).
Other: Microcrystalline cellulose placebo
Administered orally in a span of 28 days between mealtimes
Administered orally in a span of 28 days between mealtimes
To evaluate the efficacy of the intervention in improving Motivation
The mean change from baseline to day 28 of product intake across sessions in the Monetary Incentivized Delay Task (MIDT). Assessment will be recorded as number of success over total in fraction or in %
Time frame: 28 days
To evaluate the efficacy of the intervention in improving Fatigue.
Profile of Mood States short-form 2 (POMS-SF 2): change in self-reported levels of fatigue/inertia. Assessment will be recorded as score in arbitrary units (A.U.)
Time frame: 28 days
To evaluate the efficacy of the intervention in improving Fatigue.
NASA Task Load Index (NASA-TLX): changes in self-reported levels of perceived mental, physical, and temporal demands, self-perceived overall performance, levels of perceived effort exertion and levels of frustration. Assessment will be recorded as score in arbitrary units (A.U.)
Time frame: 28 days
To evaluate the efficacy of the intervention in improving Focus
Capacity to sustain high levels of attention: Psychomotor Vigilance Task. Assessment will be recorded as total number of lapses in absolute number.
Time frame: 28 days
To evaluate the efficacy of the intervention in improving Vigor.
POMS-SF 2: change in self-reported levels of vigor. Assessment will be recorded as score in arbitrary units (A.U.)
Time frame: 28 days
To evaluate the efficacy of the intervention in improving Focus
Capacity to sustain high levels of attention: Psychomotor Vigilance Task. Assessment will be recorded as reaction time in milisecond (ms)
Time frame: 28 days
To evaluate the efficacy of the intervention in improving Motivation
The mean change from baseline to day 28 of product intake across sessions in the Monetary Incentivized Delay Task (MIDT). Assessment will be recorded as effort or force in kilogram-force (kgf)
Time frame: 28 days
To evaluate the efficacy of the intervention in improving Vigor.
Self-reported motivation with the Global Motivation Scale: changes in intrinsic motivation, extrinsic motivation, and amotivation. Assessment will be recorded as score in arbitrary units (A.U.)
Time frame: 28 days
To evaluate the effect of the intervention on blood levels of vitamins B6 & B9
Change in level of vitamins B6 \& B9 in blood at baseline and Day 28 of each administration period. Assessment will be recorded in microgram per litre (µg/L).
Time frame: 28 days
To evaluate the effect of the intervention on blood levels of vitamins B12
Change in level of vitamin B12 in blood at baseline and Day 28 of each administration period. Assessment will be recorded in nanograms per litre (ng/L).
Time frame: 28 days
To evaluate the effect of the intervention on blood levels of taurine
Change in level of taurine in blood at baseline and Day 28 of each administration period. Assessment will be recorded in micromoles per litre (µmol/L)
Time frame: 28 days
Plan to share: Undecided
No publications or documents are linked to this record.
This study is completed, as verified in May 2025. You cannot join it, but the record below documents what was studied.
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Société des Produits Nestlé (SPN)