An interventional study of Pulse oximetry in Surgery and Arterial Catheterization, Peripheral, sponsored by Joseph D. Tobias. Completed at 1 site in United States. Per ClinicalTrials.gov, last updated 2026-05-13.
Sponsored by Joseph D. Tobias · Not applicable, Interventional, and Diagnostic
This is a prospective study to evaluate the feasibility of obtaining a pulse oximetry ready from the oropharynx with a standard oximeter probe that has been attached to an oral airway or a tongue blade. The study will compare the values from the peripheral pulse oximeter on a finger, toe, foot or hand with the that from the oropharyngeal oximeter. The study will also compare the saturation from an arterial blood gas (ABG) collected as standard of care with that obtained from the oropharyngeal oximeter.
Joseph D. Tobias is the lead sponsor of 28 studies on the registry; 4 are open to participants now.
Of its 6 completed or terminated interventional studies of FDA-regulated products, 6 (100%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
The use of a pulse oximeter attached to an oral airway that is in contact with the palate in the oropharynx.
Device: Pulse oximetry
The use of a pulse oximeter attached to an oral airway that is in contact with the tongue in the oropharynx.
Device: Pulse oximetry
Noninvasive method of measuring the saturation of oxygen in the blood.
Oropharyngeal vs Extremity Saturation
Difference between the average oropharyngeal oxygen saturation and the average extremity oxygen saturation which were recorded every 2 minutes for a total of 30 minutes.
Time frame: Baseline
ABG PaO2
The arterial blood gas (ABG) partial pressure of oxygen (PaO2) collected at the same time as the oropharyngeal oxygen saturation (SpO2) recording.
Time frame: Baseline
Oropharyngeal SpO2
The oropharyngeal oxygen saturation (SpO2) recorded at the same time as the arterial blood gas (ABG) partial pressure of oxygen (PaO2) collection.
Time frame: Baseline
| Milestone | Palate | Tongue |
|---|---|---|
| Started | 50 | 50 |
| Completed | 50 | 50 |
| Not completed | 0 | 0 |
Difference between the average oropharyngeal oxygen saturation and the average extremity oxygen saturation which were recorded every 2 minutes for a total of 30 minutes.
| percent of oxygen saturation | Palate | Tongue |
|---|---|---|
| Extremity | 98 (97 to 99) | 98 (97 to 99) |
| Oropharyngeal | 95 (92 to 96) | 99 (97 to 100) |
The arterial blood gas (ABG) partial pressure of oxygen (PaO2) collected at the same time as the oropharyngeal oxygen saturation (SpO2) recording.
| mmHg | Palate | Tongue |
|---|---|---|
| ABG PaO2 | 167 (135 to 210) | 237 (170 to 286) |
The oropharyngeal oxygen saturation (SpO2) recorded at the same time as the arterial blood gas (ABG) partial pressure of oxygen (PaO2) collection.
| percentage of oxygen saturation | Palate | Tongue |
|---|---|---|
| Oropharyngeal SpO2 | 100 (99.8 to 100) | 100 (100 to 100) |
Collected over Day of surgery. Non-serious events are listed at a 5% frequency threshold.
| Group | Deaths | Serious | Other |
|---|---|---|---|
| Palate | 0/50 (0%) | 0/50 (0%) | 0/50 (0%) |
| Tongue | 0/50 (0%) | 0/50 (0%) | 0/50 (0%) |
| Age, Categorical(Participants) | Palate | Tongue | Total |
|---|---|---|---|
| <=18 years | 50 | 50 | 100 |
| Between 18 and 65 years | 0 | 0 | 0 |
| >=65 years | 0 | 0 | 0 |
| Age, Continuous(years) | Palate | Tongue | Total |
|---|---|---|---|
| Median | 12 (8 to 15) | 14 (12 to 16) | 13 (9 to 15) |
| Sex: Female, Male(Participants) | Palate | Tongue | Total |
|---|---|---|---|
| Female | 30 | 27 | 57 |
| Male | 20 | 23 | 43 |
| Ethnicity (NIH/OMB)(Participants) | Palate | Tongue | Total |
|---|---|---|---|
| Hispanic or Latino | 1 | 0 | 1 |
| Not Hispanic or Latino | 49 | 50 | 99 |
| Unknown or Not Reported | 0 | 0 | 0 |
| Race (NIH/OMB)(Participants) | Palate | Tongue | Total |
|---|---|---|---|
| American Indian or Alaska Native | 0 | 0 | 0 |
| Asian | 2 | 1 | 3 |
| Native Hawaiian or Other Pacific Islander | 0 | 0 | 0 |
| Black or African American | 6 | 3 | 9 |
| White | 40 | 41 | 81 |
| More than one race | 2 | 5 | 7 |
| Unknown or Not Reported | 0 | 0 | 0 |
| Region of Enrollment(participants) | Palate | Tongue | Total |
|---|---|---|---|
| United States | 50 | 50 | 100 |
| Height(centimeters) | Palate | Tongue | Total |
|---|---|---|---|
| Median | 150 (116 to 162) | 161.5 (144 to 172) | 155 (133 to 168) |
| Weight(kilograms) | Palate | Tongue | Total |
|---|---|---|---|
| Median | 41 (23 to 61) | 52 (38 to 68) | 50 (25 to 66) |
3 further baseline measures are reported on the registry.
Documents are hosted by the registry — open the source record to download them.
Plan to share: No
This study is completed, as verified in Mar 2026. You cannot join it, but the record below documents what was studied.
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Joseph D. Tobias