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WithdrawnNCT05682625Updated Sep 19, 2024

Understanding COVID-19 Vaccine Immunity in Tissue and Blood

An observational study in COVID-19 (Coronavirus Disease 2019), sponsored by Stanford University. Withdrawn at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-09-19.

Sponsored by Stanford University · Observational

Why this study was withdrawn
Difficulty with enrollment
Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
0
Ages
18 Years and older
Sex
All
01

Study summary

The purpose of this study is to understand the effects of COVID-19 vaccines on the immune system and how the COVID-19 vaccines provide protection and induce long term memory. Adults who are receiving a COVID-19 vaccine will be invited to participate in this study.

02

Conditions studied

  • COVID-19 (Coronavirus Disease 2019)

Browse trials for

Keywords

  • Immunity
  • Vaccine
03

In context

COVID-19

7,640 studies on the registry are indexed under COVID-19; 488 are open to participants now.

Browse COVID-19 studies →

Lead sponsor

Stanford University is the lead sponsor of 2,117 studies on the registry; 425 are open to participants now.

Of its 259 completed or terminated interventional studies of FDA-regulated products, 197 (76%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Sampling method
Non-probability sample

Study population

Adults (18 years and older) receiving a COVID-19 vaccine

Inclusion criteria

  • Adults 18yrs old and higher who are receiving a COVID-19 vaccine

Exclusion criteria

Exclusion Criteria:

  • Pregnancy
  • Patients with contraindications for lymph node biopsy
  • Active cancer
  • Current use of immunosuppression drugs
05

Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
0 participants (actual)
Patient registry
No
Biospecimen retention
Samples with dna

Groups and cohorts

  • Participants

    Adults who are receiving a COVID-19 vaccine

    Other: No intervention

Interventions

  • OtherNo intervention

    No intervention

06

What researchers measure

Primary outcomes

  1. Testing immune response to the COVID-19 vaccine over time

    Time frame: 1 day

  2. Testing immune response to the COVID-19 vaccine over time

    Time frame: 7 days

  3. Testing immune response to the COVID-19 vaccine over time

    Time frame: 28 days

07

Study locations

1 site
  • Stanford University
    Palo Alto, California 94304, United States
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 19, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05682625
Lead sponsor
Stanford University
Collaborators
National Institute of Allergy and Infectious Diseases (NIAID)
Responsible party
R. Sharon Chinthrajah (Associate professor, Stanford University) — Principal investigator
First posted
Jan 12, 2023
Start date
Oct 2024 (estimated)
Primary completion
Sep 2029 (estimated)
Completion
Sep 2029 (estimated)
Last update
Sep 19, 2024

Study contacts

R. Sharon Chinthrajah, MD
principal investigator · Stanford University, Sean N. Parker Center for Allergy and Asthma Research

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is withdrawn, as verified in Sep 2024. You cannot join it, but the record below documents what was studied.

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Discussion

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