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Status unknownNCT05651854Updated Feb 22, 2023

Effect of Different Pranayama Breathing Techniques on Quality of Life in Hypertensive Patients

An interventional study of pranayama breathing in Hypertension, Stress and Aging Problems, sponsored by Cairo University. Status unknown at 1 site in Egypt. Open to participants aged 60 Years to 75 Years. Per ClinicalTrials.gov, last updated 2023-02-22.

Sponsored by Cairo University · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Dec 2022), so the status shown — last known as Recruiting — may be out of date.

From the registry’s dates

  • Registered 3 months after the study started (first participant enrolled Sep 2022, registered Dec 2022).
Phase
Not applicable
Study type
Interventional
Enrollment
60
Allocation
Randomized
Ages
60 Years to 75 Years
Sex
All
01

Study summary

The purpose of the current study is to compare between the effect of Bhramari pranayama versus Sheetali pranayama on quality of life in hypertensive patients.

Read the detailed description

People with hypertension have poorer sleep quality, less physical activity and more psychological stress than those with normal blood pressure. It has been shown that sleep affects vitality and health status and that sleep problems affect daily functioning and QOL, and so it can be assumed that in patients with hypertension, sleep problems will have a negative effect on QOL (Uchmanowicz et al., 2019).

Yogic breathing exercises are known as Pranayamas and are considered a form of meditation in itself, as well as a preparation for deep meditation. They promote physical well-being and self-awareness, improve lung and cognitive capacities, reduce blood pressure, anxiety, and other psychosomatic patterns, probably by increasing the parasympathetic tone. Pranayama alone has demonstrated numerous beneficial health effects, including stress relief, beneficial cardiovascular effect, improved respiratory function, and enhanced cognition (Jayawardena et al.,2020 ).

Since there is no study examined effect of Bhramari versus Sheetali on quality of life, physical fitness and stress in hypertensive elderly, this study aimed to examine this comparison.

02

Conditions studied

  • Hypertension
  • Stress
  • Aging Problems

Keywords

  • pranayama
  • quality of life
  • blood pressure
  • physical activity
03

In context

Lead sponsor

Cairo University is the lead sponsor of 4,780 studies on the registry; 1,427 are open to participants now.

Of its 36 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
60 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Sixty elderly are selected from both sexes. 2-Their age ranges from 60-75 years old. 3-Hypertensive patients (SBP is 140 -159 mmHg and/or DBP is 90-99 mmHg).

4-Their body mass index (BMI) ranged from \< 30kg/m2. 5-All patients are medically stable.

Exclusion criteria

Exclusion Criteria:

    • patients with cardiac problems e.g. atrial fibrillation, left bundle-branch block, heart failure, Recent myocardial infarction, coronary artery disease, or participation in cardiac rehabilitation following bypass surgery.

      2- Patients with history, symptoms of, and/or laboratory reports suggestive of renal, neurologic, or hepatic complications.

      3-Patients who have difficulty in rolling the tongue for Sheetali practice as stroke or Bell's palsy.

      4- Tongue swelling in case of acromegaly, amyloidosis, Myxedema and tongue cancer.

      5- Tongue pain in case of diabetic neuropathy, mouth ulcers, oral cancer and burn in the mouth.

      6- Chronic smokers and alcoholics. 7- Severe ear infections that interfere with bhramari breathing.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
60 participants (estimated)

Study arms

  • Experimental
    Bhramari pranayama breathing

    Bhrāmarī Prāṇāyāma breathing involves inhalation through both nostrils and producing humming sound of a bee while exhaling (Nivethitha et al., 2016).

    Other: pranayama breathing

  • Experimental
    Sheetali pranayama breathing

    Sheetali pranayama involve inhalation through extension of the tongue outside the mouth and roll the sides of the tongue up so that it would form a tube. At the end of inhalation, the tongue is drawn in, mouth is closed and exhale through the nose (Thanalakshmi et al., 2014).

    Other: pranayama breathing

Interventions

  • Otherpranayama breathing

    Bhramari and sheetali pranayama breathing

06

What researchers measure

Primary outcomes

  1. cortisol

    serum cortisol level

    Time frame: 3 months

Secondary outcomes

  1. Nitric oxide

    serum nitric oxide

    Time frame: 3 months

  2. systolic blood pressure

    systolic blood pressure

    Time frame: 3 months

  3. diastolic blood pressure

    diastolic blood pressure

    Time frame: 3 months

  4. 30 seconds sit to stand test

    physical fitness assessment

    Time frame: 3 months

  5. SF12 quality of life questionnaire

    quality of life questionnaire

    Time frame: 3 months

07

Study locations

1 of 1 sites recruiting
  • Faculty of Physical Therapy
    Dokki, Giza 12613, Egypt
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 22, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT05651854
Lead sponsor
Cairo University
Responsible party
Salma Elsayed Mohammed Elsheikh (7 ahmed elzayyat st, Dokki, Giza, Egypt., Cairo University) — Principal investigator
First posted
Dec 15, 2022
Start date
Sep 1, 2022
Primary completion
Feb 15, 2023 (estimated)
Completion
Feb 28, 2023 (estimated)
Last update
Feb 22, 2023

Study contacts

salma elsheikh, assistant lecturer
Contact
selsheikh25@yahoo.com
01118254965
Ali Esmail, lecturer
Contact
ali.mohamed@pt.cu.edu.eg
01005154209
Nesreen Elnahas, professor doctor
study chair · Cairo University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Dec 2022. You cannot join it, but the record below documents what was studied.

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