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CompletedNCT05547204Updated Mar 16, 2023

Impact of Coffeeberry Extract on Skill Performance During Simulated Match Play in Academy Football Players

An interventional study of Beverage in Skill Performance, Soccer Performance and Coffeeberry Effects, sponsored by PepsiCo Global R&D. Completed at 1 site in United Kingdom. Open to participants aged 16 Years to 28 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-03-16.

Sponsored by PepsiCo Global R&D · Not applicable, Interventional, and Basic science

Phase
Not applicable
Study type
Interventional
Enrollment
15
Allocation
Randomized
Ages
16 Years to 28 Years
Sex
All
01

Study summary

This study of soccer skill performance has three objectives:

  1. Compare effects of coffeeberry (300mg) and placebo ingestion on dribbling speed and precision, passing speed and accuracy, and sprint speed during a full simulated soccer match.
  2. Compare effects of coffeeberry (300mg) and placebo ingestion on subjective measures (mental / physical energy and activation-deactivation (feelings or mood) during a full simulated soccer match.
  3. Compare effects of coffeeberry (300mg) and placebo ingestion on chlorogenic acid (CGA) and caffeine metabolites in the blood 1-hour post ingestion, and other blood metabolites (glucose/lactate) throughout the simulated soccer match.
02

Conditions studied

  • Skill Performance
  • Soccer Performance
  • Coffeeberry Effects

Keywords

  • coffeeberry
  • caffeine
  • polyphenols
  • chlorogenic acid
  • exercise
  • soccer
  • football
  • skill
  • performance
03

In context

Lead sponsor

PepsiCo Global R&D is the lead sponsor of 101 studies on the registry; 7 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
16 Years to 28 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Provide valid informed consent prior to any study procedure
  • Male soccer players age 16 to 28 years.
  • >= 5-year soccer playing experience
  • >= 1-year regularly soccer training
  • Free of injuries
  • Willing to avoid alcohol in the 48-h period prior to all visits
  • Willing to avoid caffeinated products and apples, berries/cherries for 24-h prior to all visits
  • Willing to record food intake over the 48-h period prior to the first trial and replicate for second trial
  • Willing to abstain from strenuous physical activity for 24-h before all visits

Exclusion criteria

Exclusion Criteria:

  • Smoking
  • Cardiovascular diseases
  • Diabetes or other metabolic disease • Hypertension (>140/>90 mm Hg)
  • Presence of injuries
  • Major illnesses or surgery in prior 90 days
  • Participation in another clinical trial in the past month
05

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Randomized
Intervention model
Crossover assignment
Masking
Quadruple (Participant, Care provider, Investigator, Outcomes assessor)
Enrollment
15 participants (actual)

Study arms

  • Experimental
    Coffeeberry beverage

    300 ml drink containing 300 mg coffeeberry extract

    Other: Beverage

  • Placebo comparator
    Color and flavor matched beverage

    300 ml drink (0 mg coffeeberry extract, 0 mg caffeine)

    Other: Beverage

Interventions

  • OtherBeverage

    Free from added carbohydrates (contain 1g CHO only) and electrolytes are absent.

06

What researchers measure

Primary outcomes

  1. Dribbling speed

    m/sec, increase would be better. Simulated soccer match in an indoor gym with pre-set targets.

    Time frame: Change from pre-dose baseline through end of match 3.5 hours post consumption at multiple intervals each half of match

  2. Dribbling precision

    Meters, more accuracy would be better. Simulated soccer match in an indoor gym with pre-set targets.

    Time frame: Change from pre-dose baseline through end of match 3.5 hours post consumption at multiple intervals each half of match

  3. Passing accuracy

    1 to 10 scale, a higher score would be better. Simulated soccer match in an indoor gym with pre-set targets.

    Time frame: Change from pre-dose baseline through end of match 3.5 hours post consumption at multiple intervals each half of match.

  4. Passing speed

    km/h, increased passing speed would be better. Simulated soccer match in an indoor gym with pre-set targets.

    Time frame: Change from pre-dose baseline through end of match 3.5 hours post consumption at multiple intervals each half of match

  5. Sprint speed.

    m/sec, increased sprint speed would be better. In indoor gym with marked course.

    Time frame: Change from pre-dose baseline through end of match 3.5 hours post consumption at multiple intervals each half of match

Secondary outcomes

  1. Blood analyte: Chlorogenic acid (CGA)

    mmol/L to evaluate primary outcomes. n.a. for placebo. Capillary blood draw for frozen plasma analysis

    Time frame: Pre-dose baseline, 60 minutes post-dose, half-time, and end of match (3.5 hours)

  2. Blood analyte: Caffeine metabolites

    ug/ml, to evaluate primary outcomes. n.a. for placebo. Capillary blood draw for frozen plasma analysis

    Time frame: Pre-dose baseline, 60 minutes post-dose, half-time, and end of match (3.5 hours)

  3. Blood analyte: Glucose

    mmol/L, more regulated would be better. Capillary blood draw for frozen plasma analysis

    Time frame: Pre-dose baseline, 60 minutes post-dose, half-time, and end of match (3.5 hours)

  4. Blood analyte: Lactate

    mmol/L, lower (delayed rise) would be better. Capillary blood draw for frozen plasma analysis

    Time frame: Pre-dose baseline, 60 minutes post-dose, half-time, and end of match (3.5 hours)

  5. Rating of perceived exertion (RPE)

    By Borg scale, rated 6 to 20, very very light to very very hard. Lower values would be better

    Time frame: Half-time and end of match (3.5 hours)

  6. Activation-deactivation (feelings or mood)

    Checklist of 20 feelings using a 4 point scale from definitely do feel to definitely don't feel. More relaxed feelings or in a better mood would be better.

    Time frame: Pre-dose baseline, 60 minutes post-dose, half-time, and end of match (3.5 hours)

  7. Mental energy

    Visual Analog Scale (VAS), vertical marking on 100 mm horizontal line. Higher energy would be better

    Time frame: Pre-dose baseline, 60 minutes post-dose, half-time, and end of match (3.5 hours)

  8. Physical energy

    Visual Analog Scale (VAS), vertical marking on 100 mm horizontal line. Higher energy would be better

    Time frame: Pre-dose baseline, 60 minutes post-dose, half-time, and end of match (3.5 hours)

  9. Gut comfort

    Visual Analog Scale (VAS), vertical marking on 100 mm horizontal line. No or less nausea, fullness or bloating would be better

    Time frame: Pre-dose baseline, 60 minutes post-dose, half-time, and end of match (3.5 hours)

  10. Heart rate

    By electronic reading. Lower would be better.

    Time frame: Continuous from pre-dose baseline through end of match (3.5 hours)

  11. Hydration status

    Urine osmolality in mOsm/kg change in concentration pre- vs. post-exercise

    Time frame: Pre-dose baseline and end of match (3.5 hours)

07

Study locations

1 site
  • U. Stirling, Health Science and Sport
    Stirling, Scotland FK9 4LA, United Kingdom
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 16, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05547204
Lead sponsor
PepsiCo Global R&D
Responsible party
Sponsor
First posted
Sep 21, 2022
Start date
Jun 30, 2022
Primary completion
Dec 4, 2022
Completion
Dec 4, 2022
Last update
Mar 16, 2023

Study contacts

Stuart Galloway, PhD
principal investigator · U. Stirling, Scotland

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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