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Enrolling by invitationNCT05534516Updated Sep 9, 2026

A Study of Physiologic Changes in a Telemetry Unit

An observational study in Acute Illness Requiring to Hospital Telemetry Admission, sponsored by Mayo Clinic. Enrolling by invitation at 1 site in United States. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-09-09.

Sponsored by Mayo Clinic · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
500
Ages
18 Years to 65 Years
Sex
All
01

Study summary

The purpose of this study is to determine the physiological changes associated with health deterioration, as well as different types, doses, and routes of administration of medications and fluids in acutely ill patients.

02

Conditions studied

  • Acute Illness Requiring to Hospital Telemetry Admission
03

In context

Lead sponsor

Mayo Clinic is the lead sponsor of 3,218 studies on the registry; 670 are open to participants now.

Of its 445 completed or terminated interventional studies of FDA-regulated products, 313 (70%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Adult patients (18-65 years) admitted to the telemetry unit at Mayo Clinic Florida's Hospital with acute illness followed from admission to discharge.

Eligibility criteria

Inclusion Criteria: Mayo Clinic patients who:

  • Admitted to telemetry unit
  • With acute illness
  • Received any type of medication via any route of administration (oral, sublingual, intranasal, inhalational, intramuscular, intravenous, subcutaneous, transdermal)
  • Received any amount of any type of intravenous fluids
  • Cognitively and/or physically be able to sign consent

Exclusion Criteria:

- None

05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
500 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Change in Heart Rate

    Number of beats per minute

    Time frame: Baseline, through telemetry unit stay (approximately 1-3 days)

  2. Change in Blood Pressure

    Measured in millimeters of mercury (mmHg)

    Time frame: Baseline, through telemetry unit stay (approximately 1-3 days)

  3. Change in Respiratory Rate

    Number of breaths per minute

    Time frame: Baseline, through telemetry unit stay (approximately 1-3 days)

  4. Change in Oxygen Saturation Levels

    Measured by a pulse oximeter reading reported as a percentage

    Time frame: Baseline, through telemetry unit stay (approximately 1-3 days)

  5. Change in ECG morphology

    Changes in ECG waveform appearance measured from the digital ECG waveform interpretation

    Time frame: Baseline, through telemetry unit stay (approximately 1-3 days)

07

Study locations

1 site
  • Mayo Clinic Florida
    Jacksonville, Florida 32224, United States
08

References and documents

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 9, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05534516
Lead sponsor
Mayo Clinic
Responsible party
Antonio J. Forte (Principal Investigator, Mayo Clinic) — Principal investigator
First posted
Sep 9, 2022
Start date
Feb 22, 2023
Primary completion
Aug 2028 (estimated)
Completion
Aug 2029 (estimated)
Last update
Sep 9, 2026

Study contacts

Antonio Forte, MD, PhD
principal investigator · Mayo Clinic

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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No contact was published for this record. The registry link below has the sponsor’s details.

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