An interventional study of Description of Slow pathway signals to facilitate ablation in Supraventricular Tachycardia and Atrioventricular Nodal Re Entrant Tachycardia, sponsored by Parc de Salut Mar. Completed at 1 site in Spain. Open to participants aged 18 Years to 90 Years. Per ClinicalTrials.gov, last updated 2024-04-12.
Sponsored by Parc de Salut Mar · Not applicable, Interventional, and Treatment
Atrioventricular nodal reentrant tachycardia (AVNRT) is the most common supraventricular tachycardia inducible during an electrophysiological study. Although ablative therapy proved to be the treatment of choice, little is known about the components of the tachycardia circuit. The aim of this study is to detect the presence and patterns of specific electrograms representing slow pathway (SP) potentials and to explore Koch's triangle pattern activation during sinus rhythm and/or atrial extraestimulus with a high-density mapping catheter in an attempt to clarify a fast and safety catheter ablation strategy. We hypothesized that, in patients with dual atrioventricular nodal physiology, during sinus rhythm (SR), high-density mapping (HDM) catheters could identify the SP signals, making possible to delineate small areas of slow conduction associated to abnormal electrograms on Koch's triangle. On a second step, radiofrequency (RF) applications safety guided by the HDM obtained with this method, should interrupt the circuit far from the His region. Finally, SP signals should disappear after the RF procedure when performing a new 3D HDM. A control group of patients without AVN dual physiology should show absence of fragmented/slow conduction zones.
623 studies on the registry are indexed under Tachycardia; 81 are open to participants now.
This study's enrollment of 119 is above the median of 64 across 379 interventional studies indexed under Tachycardia.
Browse Tachycardia studies →Parc de Salut Mar is the lead sponsor of 180 studies on the registry; 27 are open to participants now.
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Exclusion Criteria:
Patient with documented AVNRT and fragmented/slow conduction zones observed in a 3D high density mapping
Device: Description of Slow pathway signals to facilitate ablation
3D endocardial mapping in order to identify slow pathway signals and abolish or modificate them after radiofrequency ablation
Absence of reinduction of AVNRT after abolition of fragmented/slow conduction signals
Number of patients with absence of fragmented/slow conduction signals observed during sinus rhythm or atrial pacing after radiofrequency application
Time frame: one day
Absence of AVNRT relapses
Number of patients with absence of relapses after 1 month of the electrophysiological study
Time frame: one month
Percentage of patient without AVNRT reinduction after procedure
Percentage of patients without tachycardia induction after radiofrequency applications protocol
Time frame: One day
Plan to share: No — Data will be register with RED CAP
No publications or documents are linked to this record.
This study is completed, as verified in Apr 2024. You cannot join it, but the record below documents what was studied.
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Parc de Salut Mar