An observational study in Placenta Accreta Spectrum, sponsored by Sohag University. Status unknown at 1 site in Egypt. Open to female participants aged Up to 51 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-08-22.
Sponsored by Sohag University · Observational
The objective of this study is to evaluate different intra-operative procedures to control bleeding in cases of PAS disorders aiming to determine the best procedure regarding maternal morbidity and mortality post-operatively, and to evaluate the long-term effects of conservative management of PAS disorders.
The term "placenta accreta spectrum" (PAS), formerly known as "morbidly adherent placenta" or "abnormally invasive placenta," refers to the aberrant trophoblast invasion of all or a portion of the placenta into the myometrium of the uterus. according to the depth of the villous invasion into the myometrium, the spectrum is assorted into three groups: placenta accreta (villi attach to the myometrium without invading it), placenta increta (villi infiltrate the myometrium), and placenta percreta (villi pierce through the uterine serosa and may infiltrate the surrounding tissues). The optimal strategy for managing PAS disorders remains debatable. Conservative management of PAS disorders includes all techniques aimed at preserving the uterus. Because intraoperative bleeding from PAS disorders is frequently massive and dramatic, causing severe maternal morbidity and mortality, it is essential to have a well-planned, effective, and rapid approach to this surgical challenge.
147 studies on the registry are indexed under Placenta Accreta; 39 are open to participants now.
This study's planned enrollment of 60 is below the median of 84 across 79 observational studies indexed under Placenta Accreta.
Browse Placenta Accreta studies →Sohag University is the lead sponsor of 1,182 studies on the registry; 611 are open to participants now.
Counted across the registry records on this site, refreshed daily.
community sample, any suspected case of PAS disorders.
Exclusion Criteria:
in which full-thickness vertical compression suture combined with inflated intrauterine balloon are used to control bleeding
in this group, a resective-reconstructive technique is used, which involves resecting the invasive accreta area followed by immediate uterine reconstruction and bladder reinforcement
In this group, bilateral uterine artery ligations combined with cervical tamponade which is performed by elevating the cervix into the uterine cavity with Allis forceps, then suturing the anterior and/ or posterior cervical lip(s) into the anterior and/ or posterior uterine segment(s) depending on the site of bleeding with two or three simple interrupted stitches, with the patency of the cervical canal confirmed, followed by closure of the uterine incision
successful intervention procedure
Preservation of the uterus
Time frame: 1 day
maternal mortality and morbidity
ICU admission, need of re-exploration, drop of hemoglobin and hematocrit values, massive blood transfusion, bladder and/ or ureteric injury, coagulopathy, infection and hospital re-admission within 6 weeks
Time frame: 6 weeks
Plan to share: Undecided
No publications or documents are linked to this record.
This study is status unknown, as verified in Aug 2022. You cannot join it, but the record below documents what was studied.
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Sohag University