CClinicalTrials.gg
Status unknownNCT05506527Updated Aug 18, 2022

Assessment of Respiratory Function Cerebral Palsy Using Plyometric Exercise Sensorimotor Program

An interventional study of Sensorimotor program and plyometric exercise in Cerebral Palsy, sponsored by Egyptian Chinese University. Status unknown at 1 site in Egypt. Open to participants aged 8 Years to 14 Years. Per ClinicalTrials.gov, last updated 2022-08-18.

Sponsored by Egyptian Chinese University · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Aug 2022), so the status shown — last known as Not yet recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Randomized
Ages
8 Years to 14 Years
Sex
All
01

Study summary

To examine if adding plyometric exercises to sensorimotor exercises would improve respiratory function in children and adolescents with cerebral palsy

Read the detailed description

Cerebral palsy (CP) is a varied group of developmental disorders secondary to a static immature brain injury that primarily results in persistent nonspecific impairment of movement and posture. Approximately 25% of all CP cases experience disturbance of motor function with unilateral spasticity pertaining to the upper and lower extremities contralateral to the affected cerebral hemisphere and categorized as spastic hemiplegia. Some asymmetries might be noted when hemiplegic children are attempting to perform motor activities. In supported standing, hemiplegic children may stand preferentially on their more functional side and exhibit postural malalignments that impair the ability to transfer body weight on the affected lower extremity.

Children and adolescents with CP have poor respiratory function, secondary to the disease process. Impaired airway clearance, recurrent aspirations, chest infections, poor cough mechanism, impaired lung function, deformity of the spine and chest, and poor nutrition status influence the respiratory condition of children and adults with CP resulting in reduced lung capacity in these individuals.

Plyometric exercises are a specific pattern of resistive strength training in which the muscle starts to contract eccentrically followed by rapid concentric contraction of the same muscle. It can jointly generate high velocity dynamic movements and high-impact force on the muscles and bones. Currently, a limited number of studies have analysed the efficacy of the plyometric training on respiratory function in children with CP or any other disabling health conditions. Preliminary studies have demonstrated the positive effect of plyometric exercises for the gross motor function in boys with unilateral CP.

02

Conditions studied

  • Cerebral Palsy

Keywords

  • respiratory capacity
  • cerebral palsy
  • plyometric exercise
03

In context

Paralysis

750 studies on the registry are indexed under Paralysis; 133 are open to participants now.

This study's planned enrollment of 40 is above the median of 30 across 537 interventional studies indexed under Paralysis.

Browse Paralysis studies →

Lead sponsor

Egyptian Chinese University is the lead sponsor of 8 studies on the registry; 1 is open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
8 Years to 14 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Age will be 8 - 14 years.
  • children will be assigned to the study are suffering from spastic hemiplegic cerebral palsy (less than grade 1+ om Modified Ashwar Scale)
  • Considering the physical problems, children will be chosen according to Growth Motor Function Classification System (GMFCS) with levels I-III
  • The ability to understand simple verbal instructions.

Exclusion criteria

Exclusion Criteria:

  • Visual and hearing impairment; surgery within the last three months preventing them from taking part in sensorimotor physical therapy
  • Severe oromotor issues
  • Severe chest infections
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
40 participants (estimated)

Study arms

  • Experimental
    study group 1

    Study group A: will receive combined plyometric exercises and sensorimotor program

    Other: Sensorimotor program and plyometric exercise

  • Experimental
    study group 2

    Study group B: will receive sensorimotor program alone

    Other: Sensorimotor program and plyometric exercise

Interventions

  • OtherSensorimotor program and plyometric exercise

    Children in study group A will receive combined plyometric exercises (vertical paradigm) and sensorimotor program - Children of the study group B will receive sensorimotor program alone.

06

What researchers measure

Primary outcomes

  1. change of spasticity

    will be measured by modified Ashower Scale

    Time frame: six weeks

Secondary outcomes

  1. change of Respiratory capacity and vital capacity

    will be measured by incentive spirometry

    Time frame: six weeks

07

Study locations

1 site
  • Cairo University
    Giza, 12613, Egypt
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 18, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05506527
Lead sponsor
Egyptian Chinese University
Responsible party
Mohamed Abdelmoneim El Meligy (lecturer of physical therapy for pediatrics, Egyptian Chinese University) — Principal investigator
First posted
Aug 18, 2022
Start date
Sep 1, 2022 (estimated)
Primary completion
Oct 1, 2022 (estimated)
Completion
Jan 1, 2023 (estimated)
Last update
Aug 18, 2022

Study contacts

Mohamed Abo-El-Ros, Ph.D
Contact
maboelroose@ecu.edu.eg
+201206530584
Marian Fayez, Ph.D
Contact
mfayez@ecu.edu.eg
+201222748287
Eman Abdel-Halim
study director · Cairo University

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Aug 2022. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion