An observational study in Carrier State and Respiratory Infections, sponsored by Philip Polgreen. Recruiting at 1 site in United States. Open to participants aged 18 Years to 100 Years. Per ClinicalTrials.gov, last updated 2026-09-04.
Sponsored by Philip Polgreen · Observational
A research team member will brush the inferior surface of the subjects' middle turbinate (nasal cavity) using a cytology brush to obtain the cells needed to perform our functional respiratory assays.
An individual trained in phlebotomy will draw one 3 ml lavender top tube of blood to test c-reactive protein, calprotectin, and lactoferrin. They will also draw a 5 ml gold top serum separator tube of blood to test fibroblast growth factor-19.
The participant will answer questions from the baseline survey and report their current medications interview-style with the research team member.
1,031 studies on the registry are indexed under Respiratory Tract Infections; 144 are open to participants now.
This study's planned enrollment of 160 is below the median of 300 across 295 observational studies indexed under Respiratory Tract Infections.
Browse Respiratory Tract Infections studies →Philip Polgreen is the lead sponsor of 3 studies on the registry; 2 are open to participants now.
Counted across the registry records on this site, refreshed daily.
CF Carriers and Controls who are not CF carriers.
CF Carrier Inclusion Criteria:
Control Group Inclusion Criteria:
Exclusion Criteria:
Participants have been identified as Cystic Fibrosis Carriers via previous genetic testing.
Participants have been identified as not being Cystic Fibrosis Carriers via previous genetic testing.
Comparison of Chloride Transport Values
Comparison of chloride transport values in cystic fibrosis carrier group vs control group via t-test.
Time frame: At baseline
Comparison of Bicarbonate Transport Values
Comparison of bicarbonate transport values in cystic fibrosis carrier group vs control group via t-test.
Time frame: At baseline
Comparison of Airway Surface Liquid pH Values
Comparison of airway surface liquid pH values in cystic fibrosis carrier group vs control group via t-test.
Time frame: At baseline
Comparison of Mucous Viscosity Values
Comparison of mucous viscosity values in cystic fibrosis carrier group vs control group via t-test.
Time frame: At baseline
Comparison of Bacterial Killing Values
Comparison of bacterial killing values in cystic fibrosis carrier group vs control group via t-test.
Time frame: At baseline
Comparison of Fibroblast Growth Factor-19 Values
Comparison of fibroblast growth factor-19 values in cystic fibrosis carrier group vs control group via t-test.
Time frame: At baseline
Plan to share: No
No publications or documents are linked to this record.
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