An observational study in Pregnancy Complications, Perinatal Problems and Maternal-Fetal Relations, sponsored by Siirt University. Completed at 1 site in Turkey. Open to female participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-04-25.
Sponsored by Siirt University · Observational
It has been known for years that placental transport and endocrine and metabolic functions of the placenta are the main determinants of fetal nutrition and homeostasis. And placental capacity is roughly related to the weight of this organ. It has long been understood that placental weight at birth is also positively associated with birth weight. Since the 1970s, it has been possible to assess the size of the placenta in early pregnancy using two-dimensional (2D) ultrasonography (USG). Since then, it has been estimated that placental size is associated with fetal development. However, the difficulty in defining the required sonographic planes due to the technology of that time-limited the usefulness of this technique. As studies on this subject increase with the development of technology, it has now been shown that low placental volume at 11-13 weeks is associated with babies small for gestational age (SGA), fetal growth restriction, and preeclampsia. Pregnancy complications place a severe burden on the health system. Detection of these complications in the early period will prevent maternal and fetal mortality and morbidity. A relationship that predicts obstetric, fetal, and perinatal risks with placental thickness and width measurement with USG, a non-invasive method, in an early period such as the 1st trimester, will enable a proactive approach to complications. In our study, the investigators plan to present the perinatal results they obtained rather than investigating a specific relationship. The investigators think that the results of their study will make a profound contribution to the literature.
This study aims to determine the relationship between the calculated placental volume in the 1st trimester and poor perinatal outcomes. For this purpose, approximately 360 pregnant women, who were followed up in Siirt Training and Research Hospital between June 2022 and June 2023 and were in their first trimester of pregnancy, will be included in the study. The pregnant woman's age, pregnancy history, and medical history will be recorded. The patient's gestational week, placental volume, and location will be recorded during the examination. All participants will be followed up until delivery. During delivery, gestational week, delivery type, fetal weight, APGAR score, baby gender, and pregnancy outcomes, preeclampsia, Gestational Diabetes, Gestational Hypertensive diseases, Premature rupture of membranes, preterm labor, oligohydramnios, polyhydramnios, presentation anomaly, Intrauterine death, Perinatal fetal disorders such as distress, intrauterine growth retardation, preeclampsia, placental abruption, placental invasion anomaly, placental implantation anomalies, postmaturity will be recorded. In the light of the information gathered, the relationship between placental volume in the 1st trimester and perinatal prognosis will be determined.
437 studies on the registry are indexed under Pregnancy Complications; 119 are open to participants now.
This study's enrollment of 360 is above the median of 320 across 205 observational studies indexed under Pregnancy Complications.
Browse Pregnancy Complications studies →Siirt University is the lead sponsor of 16 studies on the registry; 2 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Pregnant women over the age of 18 and at 11-14 weeks of pregnancy
Exclusion Criteria:
Measurement of placental volume at the first trimester of pregnancy by using ultrasound.
Placental thickness in millimetres and pregnancy outcomes
The relationship between placental volume in the 1st trimester and perinatal prognosis will be tried to be determined.
Time frame: From the 1.st trimester of pregnancy up to the first month after birth ( the perinatal period,(( about 7 months ))
Pregnancy outcomes
Gestational age in weeks during delivery
Time frame: Pregnancy Week at the time of birth from the first three -month period of pregnancy (about 7 months)
Pregnancy outcomes
Fetal weight in grams
Time frame: Fetal weight at the time of birth from the first three -month period of pregnancy (about 7 months)
Pregnancy outcomes
APGAR scores in numerical values
Time frame: At the first minute and 5th minute after delivery
This study is completed, as verified in Apr 2023. You cannot join it, but the record below documents what was studied.
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Siirt University