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CompletedNCT05394870Updated Jul 6, 2022

Clinical and Electrophysiological Evaluation of the Effectiveness for Manual Lymphatic Drainage

An interventional study of manual lymphatic drainage (massage) and Splint treatment in Carpal Tunnel Syndrome, Electrophysical Evaluation and Manual Lymphatic Drainage, sponsored by Selcuk University. Completed at 1 site in Turkey. Open to participants aged 20 Years to 55 Years. Per ClinicalTrials.gov, last updated 2022-07-06.

Sponsored by Selcuk University · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
34
Allocation
Randomized
Ages
20 Years to 55 Years
Sex
All
01

Study summary

When the other usage areas of the manual lymphatic drainage technique in the literature, except for the treatment of lymphedema, were examined recently, it was seen that it was also applied in orthopedic and neurological cases in a limited number of studies. The aim of our study is to investigate the effectiveness of manual lymphatic drainage on clinical and electrophysiological findings in carpal tunnel syndrome

02

Conditions studied

  • Carpal Tunnel Syndrome
  • Electrophysical Evaluation
  • Manual Lymphatic Drainage
03

In context

Carpal Tunnel Syndrome

589 studies on the registry are indexed under Carpal Tunnel Syndrome; 139 are open to participants now.

This study's enrollment of 34 is below the median of 60 across 445 interventional studies indexed under Carpal Tunnel Syndrome.

Browse Carpal Tunnel Syndrome studies →

Lead sponsor

Selcuk University is the lead sponsor of 248 studies on the registry; 63 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 55 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Diagnosis of mild to moderate carpal tunnel syndrome on electrodiagnostic examination
  • Being between 20-55 years old
  • Volunteering to participate in the treatment to be given

Exclusion criteria

Exclusion Criteria:

  • Have a systemic inflammatory disease
  • Having any disease that may cause polyneuropathy, such as diabetes mellitus
  • Cognitive impairment
  • Receiving psychotherapy
  • Having a pacemaker
  • illiterate
  • Having a disease affecting the central nervous system
  • Having a hearing problem
  • Any skin disease that would contraindicate manual lymphatic drainage
  • Arterial or venous circulation disorder that would contraindicate manual lymphatic drainage
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
34 participants (actual)

Study arms

  • Experimental
    study group

    Other: manual lymphatic drainage (massage) · Other: Splint treatment

  • Active comparator
    control group

    Other: Splint treatment

Interventions

  • Othermanual lymphatic drainage (massage)

    Patients will begin treatment with manual lymphatic drainage in the affected extremity. In this context, while the patients are in the supine hook position, lymph drainage will be applied first to the neck and then to the abdomen. After the stimulation of the central lymph nodes, the lymph circulation will be increased by stimulating the axillary lymph nodes of the relevant region. First, the proximal part will be drained and it will be advanced towards the distal. Drainage will be repeated depending on the edema at the distal forearm-wrist level.

  • OtherSplint treatment

    The splint routinely given to patients diagnosed with mild to moderate carpal tunnel syndrome will be given to both groups in these patients

06

What researchers measure

Primary outcomes

  1. pressure pain threshold

    Each evaluation will be repeated 3 times with 10 seconds between measurements, and the data will be recorded by taking the average of the last two measurements (15). The patients will be evaluated by measuring the transverse carpal ligament, radioulnar joint and extensor digitorum muscle with an algometer before and at the end of the treatment. measurements will be recorded in kg/cm2

    Time frame: 15 minutes

  2. Boston Carpal Tunnel Questionnaire (BCTQ)

    BCTQ, a self-report measure of CTS, evaluates two domains: 1. The symptom severity scale (BCTQSS) has 11 items that assess pain, paresthesia, and weakness. 2. The functional status scale (BCTQ-FS) evaluates the ability to perform manual activities with 8 items. Each item evaluates the increasing severity of symptoms or difficulty with a high score.

    Time frame: 10 minutes

  3. Electrodiagnostic evaluation

    Median motor nerve latency, median motor nerve conduction velocity, compound muscle action potential amplitude will be measured at both levels. Median sensory nerve conduction studies will be performed by antidromic recording with a superficial electrode from the 3rd finger and a stimulus will be given from the wrist 14 cm proximal. Median sensory nerve latency, median sensory nerve conduction velocity and sensory nerve action potential will be calculated for both applications. nerve potentials will be calculated in m/sec

    Time frame: 15 minutes

07

Study locations

1 site
  • Kutahya Health Science University
    Kütahya, Centrum 43040, Turkey
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 6, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT05394870
Lead sponsor
Selcuk University
Responsible party
Emine Cihan (Lecturer, Selcuk University) — Principal investigator
First posted
May 27, 2022
Start date
Apr 1, 2022
Primary completion
Jun 1, 2022
Completion
Jun 10, 2022
Last update
Jul 6, 2022

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Jul 2022. You cannot join it, but the record below documents what was studied.

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