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CompletedNCT05366491Updated May 12, 2022

IL-38 Evaluation as a Biomarker in Pediatric Asthma

An interventional study of Il-38 serum level in Bronchial Asthma, sponsored by Cairo University. Completed at 1 site in Egypt. Open to participants aged 6 Years to 14 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-05-12.

Sponsored by Cairo University · Not applicable, Interventional, and Diagnostic

From the registry’s dates

  • Registered 1 year 9 months after the study started (first participant enrolled Aug 2020, registered May 2022).
Phase
Not applicable
Study type
Interventional
Enrollment
103
Allocation
Non-randomized
Ages
6 Years to 14 Years
Sex
All
01

Study summary

The aim of this study is to investigate the associations between serum IL-38 levels and different variables of asthma in children such as laboratory variables, pulmonary function test results, the diagnosis of asthma, and in correlation with disease severity.

02

Conditions studied

  • Bronchial Asthma

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03

In context

Asthma

3,921 studies on the registry are indexed under Asthma; 507 are open to participants now.

This study's enrollment of 103 is above the median of 83 across 2,752 interventional studies indexed under Asthma.

Browse Asthma studies →

Lead sponsor

Cairo University is the lead sponsor of 4,780 studies on the registry; 1,427 are open to participants now.

Of its 36 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
6 Years to 14 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • patients fulfilled the criteria of the Global Initiative for Asthma (GINA)
  • Age group:6-14 years

Exclusion criteria

Exclusion Criteria:

  • Malignancy
  • Chronic inflammatory diseases
05

Study design

Phase
Not applicable
Primary purpose
Diagnostic
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
103 participants (actual)

Study arms

  • Active comparator
    bronchial asthma patients

    patients diagnosed with bronchial asthma

    Diagnostic Test: Il-38 serum level

  • Active comparator
    healthy controls

    healthy subjects with age and sex matched to bronchial asthma patients

    Diagnostic Test: Il-38 serum level

Interventions

  • Diagnostic testIl-38 serum level

    measurement of serum levels of IL-38

06

What researchers measure

Primary outcomes

  1. serum IL-38 levels

    Measurement of Interleukin 38 in sera of all study subjects by ELISA

    Time frame: within 6 months

07

Study locations

1 site
  • Asmaa Kamal
    Cairo, 11562, Egypt
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 12, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05366491
Lead sponsor
Cairo University
Responsible party
Asmaa Mohamed Kamal (Assistant professor, Cairo University) — Principal investigator
First posted
May 9, 2022
Start date
Aug 1, 2020
Primary completion
Jan 12, 2021
Completion
Apr 15, 2021
Last update
May 12, 2022

Study contacts

Asmaa Kamal, Ass prof
principal investigator · Assistant professor

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in May 2022. You cannot join it, but the record below documents what was studied.

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