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Status unknownNCT05360875Updated May 4, 2022

The Effect of Endometrial Scratching on Patients With Endometriosis

An interventional study of Endometrial scratching in Endometriosis and IVF, sponsored by Peking Union Medical College Hospital. Status unknown at 1 site in China. Open to female participants aged 22 Years to 40 Years. Per ClinicalTrials.gov, last updated 2022-05-04.

Sponsored by Peking Union Medical College Hospital · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified May 2022), so the status shown — last known as Recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
80
Allocation
Non-randomized
Ages
22 Years to 40 Years
Sex
Female
01

Study summary

We aimed to investigate whether endometrial scratching could improve IVF outcomes by enhancing endometrial receptivity in patients with endometriosis.

02

Conditions studied

  • Endometriosis
  • IVF

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Keywords

  • Endometriosis
  • Endometrial scratching
  • Endometrial receptivity
  • IVF
  • Pregnancy rates
03

In context

Endometriosis

901 studies on the registry are indexed under Endometriosis; 259 are open to participants now.

This study's planned enrollment of 80 is above the median of 64 across 525 interventional studies indexed under Endometriosis.

Browse Endometriosis studies →

Lead sponsor

Peking Union Medical College Hospital is the lead sponsor of 1,115 studies on the registry; 463 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
22 Years to 40 Years
Sexes eligible
Female
Accepts healthy volunteers
No

Inclusion criteria

1.Endometriosis that surgery or pathology confirmed; 2. normal ovarian reserve; 3. at least one implantation failure history

Exclusion criteria

Exclusion Criteria:

  1. hydrosalpinx; 2.ademomyosis; 3.endocrine or self-immune disease; 4.serious medical condition; 5.Contraindications of intrauterine operation
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Non-randomized
Intervention model
Single group
Masking
None (open label)
Enrollment
80 participants (estimated)

Study arms

  • Experimental
    Endometrial scratching group

    Procedure: Endometrial scratching

  • No intervention
    Non-scratching group

Interventions

  • ProcedureEndometrial scratching

    An intrauterine procedure that causes mild endometrial injury

06

What researchers measure

Primary outcomes

  1. clinical pregnancy rate

    pregnancy sacs confirmed by ultrasound

    Time frame: 6-7 weeks of gestation

07

Study locations

1 of 1 sites recruiting
  • Peking Union Medical College Hospital
    Beijing, Beijing 100730, China
    Recruiting
08

References and documents

Individual participant data

Plan to share: Yes

Supporting information: Study protocol

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 4, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05360875
Lead sponsor
Peking Union Medical College Hospital
Responsible party
Qi Yu (professor, Peking Union Medical College Hospital) — Principal investigator
First posted
May 4, 2022
Start date
May 1, 2022
Primary completion
Apr 30, 2023 (estimated)
Completion
Jun 30, 2023 (estimated)
Last update
May 4, 2022

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in May 2022. You cannot join it, but the record below documents what was studied.

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Discussion

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