An observational study in Endometriosis, sponsored by Bagcilar Training and Research Hospital. Completed at 1 site in Turkey. Open to female participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-04-05.
Sponsored by Bagcilar Training and Research Hospital · Observational
The diagnostic value of Annexin V, sVCAM-1, sICAM-1, vascular endothelial growth factor and Proinflammatory cytokines (TNF-a and interleukin-6) in ovarian endometriosis and deep infiltrating endometriosis, their levels in organ-specific involvement, their relationship with symptoms, and the changes of these markers in the postoperative period will be evaluated.
Serum Annexin V, sVCAM-1, sICAM-1, vascular endothelial growth factor and proinflammatory cytokines (TNF-a and interleukin-6) values were studied by taking blood samples from all patients before and three months after the operation.
901 studies on the registry are indexed under Endometriosis; 259 are open to participants now.
This study's enrollment of 79 is below the median of 128 across 344 observational studies indexed under Endometriosis.
Browse Endometriosis studies →Bagcilar Training and Research Hospital is the lead sponsor of 54 studies on the registry; 6 are open to participants now.
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Stage III and IV endometriosis patients aged 18-50 years requiring surgery for chronic pelvic pain or suspected malignancy
Exclusion Criteria:
Stage 3 and 4 endometriosis patients
Procedure: endometriosis surgery
Patients without endometriosis, who required surgery for tubal ligation, benign ovarian cysts or uterine fibroids were included.
Procedure: other benign condition surgeries
Laparoscopy was performed in the follicular phase of the woman's menstrual cycle and all recognizable endometriotic lesions were treated by bipolar coagulation, resection of endometriotic nodules and ovarian cystectomy.
ovarian cystectomy, bilateral tubal ligation, myomectomy etc.
Diagnostic value of serum Annexin V in endometriosis
To determine whether serum Annexin V levels (ng/mL) can be used as diagnostic markers of endometriosis disease.
Time frame: Up to 4 months
Diagnostic value of serum sVCAM-1 in endometriosis
To determine whether serum sVCAM-1(ng/mL) levels can be used as diagnostic markers of endometriosis disease.
Time frame: Up to 4 months
Diagnostic value of serum sICAM-1 in endometriosis
To determine whether serum sICAM-1(ng/mL) levels can be used as diagnostic markers of endometriosis disease.
Time frame: Up to 4 months
Diagnostic value of serum Vascular Endothelial Growth Factor in endometriosis
To determine whether serum Vascular Endothelial Growth Factor (pg/mL) levels can be used as diagnostic markers of endometriosis disease.
Time frame: Up to 4 months
Diagnostic value of serum TNF-alpha in endometriosis
To determine whether serum TNF-alpha (pg/mL) levels can be used as diagnostic markers of endometriosis disease.
Time frame: Up to 4 months
Diagnostic value of serum Interleukin-6 in endometriosis
To determine whether serum Interleukin-6 (pg/mL) levels can be used as diagnostic markers of endometriosis disease.
Time frame: Up to 4 months
Plan to share: No
This study is completed, as verified in Mar 2022. You cannot join it, but the record below documents what was studied.
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Bagcilar Training and Research Hospital