CClinicalTrials.gg
Status unknownNCT05301075Updated Mar 29, 2022

Rhomboid Intercostal and Subserratus Plane (RISS) Block on Postoperative Painafter Open Nephrectomy Surgery

An Early Phase 1 interventional study of Rhomboid Intercostal and Sub-Serratus block in Rhomboid Intercostal Block, sponsored by Cairo University. Status unknown at 1 site in Egypt. Open to participants aged 18 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-03-29.

Sponsored by Cairo University · Early Phase 1, Interventional, and Diagnostic

The sponsor has not verified this record recently (last verified Mar 2022), so the status shown — last known as Enrolling by invitation — may be out of date.
Phase
Early Phase 1
Study type
Interventional
Enrollment
60
Allocation
Randomized
Ages
18 Years to 60 Years
Sex
All
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Study summary

Rhomboid intercostal block (RIB) is a new interfascial plane block describe by Elsharkawy et al. in 2016. The region described is understood because the triangle of auscultation that's bounded medially by inferior a part of the trapezius, inferiorly by the superior border of latissimus dorsi, and laterally by the medial border of the scapula. In this ultrasound-guided block, the local anaesthetic drug is run between the rhomboid major and therefore the intercostal fascia at the extent of T6-T7 and provides analgesia of T3-T8 dermatomes

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Conditions studied

  • Rhomboid Intercostal Block
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In context

Lead sponsor

Cairo University is the lead sponsor of 4,780 studies on the registry; 1,427 are open to participants now.

Of its 36 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Eligibility criteria

  • Inclusion criteria Adult patients between 18-60 years. Genders eligible for study: both sexes ASA physical status I and II Undergoing open nephrectomy surgery
  • Exclusion criteria Patient refusal Contraindications to regional anesthesia Known allergy to local anesthetics Bleeding disorders Use of any anti-coagulants Inability to provide informed consent ASA III-IV
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Study design

Phase
Early Phase 1
Primary purpose
Diagnostic
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Quadruple (Participant, Care provider, Investigator, Outcomes assessor)
Enrollment
60 participants (estimated)

Study arms

  • Sham comparator
    control group

    patients will receive sham block.

    Drug: Rhomboid Intercostal and Sub-Serratus block

  • Active comparator
    RISS group

    will receive Rhomboid Intercostal and Sub-Serratus block under ultrasound guidance

    Drug: Rhomboid Intercostal and Sub-Serratus block

Interventions

  • DrugRhomboid Intercostal and Sub-Serratus block

    Rhomboid Intercostal and Sub-Serratus block under ultrasound guidance

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What researchers measure

Primary outcomes

  1. nalbuphine consumption i

    Postoperative nalbuphine consumption

    Time frame: 24 hours

Secondary outcomes

  1. nalbuphine consumption.

    intraoperative nalbuphine consumption.

    Time frame: 2 hours

  2. Patient's satisfaction

    using 1-4 scales (1, bad; 2, moderate; 3, good; 4, excellent;

    Time frame: 24 hours

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Study locations

1 site
  • Cairo university
    Cairo, 11562, Egypt
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References and documents

Individual participant data

Plan to share: Undecided — still working

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 29, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05301075
Lead sponsor
Cairo University
Responsible party
Amr Samir Wahdan (Lecturer of Anesthesia, Pain management and Surgical ICU, Cairo University) — Principal investigator
First posted
Mar 29, 2022
Start date
Mar 21, 2022 (estimated)
Primary completion
Aug 13, 2023 (estimated)
Completion
Aug 30, 2023 (estimated)
Last update
Mar 29, 2022

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Mar 2022. You cannot join it, but the record below documents what was studied.

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