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Status unknownNCT05263687Updated Mar 21, 2022

Exercise Testing in Diseases and Health

An interventional study of Maximal exercise test in Exercise Test, sponsored by The Baruch Padeh Medical Center, Poriya. Status unknown at 1 site in Israel. Open to participants aged 4 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-03-21.

Sponsored by The Baruch Padeh Medical Center, Poriya · Not applicable, Interventional, and Diagnostic

The sponsor has not verified this record recently (last verified Mar 2022), so the status shown — last known as Recruiting — may be out of date.

From the registry’s dates

  • Registered 4 years 5 months after the study started (first participant enrolled Aug 2017, registered Feb 2022).
Phase
Not applicable
Study type
Interventional
Enrollment
1,000
Allocation
Not applicable
Ages
4 Years to 80 Years
Sex
All
01

Study summary

Cardiopulmonary exercise test (CPET) is a helpful tool for evaluation of aerobic exercise capacity and tolerance for variety of population. CPET provides a full assessment of the physiologic responses of the pulmonary, cardiovascular, muscular, and cellular oxidative systems to exercise. The test progression include a incremental stepwise (on treadmill) or ramp control protocol (on bike ergometer ) to exhaustion. Measurement of respiratory gas exchange i.e. oxygen uptake, carbon dioxide, minute ventilation, other variables while monitoring ECG, blood pressure, pulse oximetry and exertion perceived (Borg Scale) during an incremental test .

Aim: To compere exercise responses for maximal exercise testing with different population.

Read the detailed description

Each participants will conducted an exercise test on treadmill using Modified Bruce Protocol) or cycle ergometer. Quark CPET metabolic cart (Cosmed, Rome, Italy) will be use to collect and analysis gas exchange. 10 minute after the graded exercise test Supra maximal exercise test (SMT) will be done for 2 minutes one stage (treadmill protocol) or 10% at cycle protocol higher than highest load achieved in the incremental test.

all outcome measurement will be collected. Exercise tolerance and responses will be assess using the data of : pulmonary gas exchange; cardiovascular performance, and skeletal muscle metabolism.

02

Conditions studied

  • Exercise Test
03

In context

Lead sponsor

The Baruch Padeh Medical Center, Poriya is the lead sponsor of 41 studies on the registry; 2 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
4 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

*Patient who invited to the clinic to do incremental maximal exercise test or healthy *Participants with no known significant health problems.

Exclusion criteria

Exclusion Criteria:

  • Acute fever
  • Acute myocardial infarction within 2 to 3 days.
  • Unstable angina not previously stabilized by medical therapy.
  • Uncontrolled cardiac arrhythmias causing symptoms or hemodynamic compromise.
  • Symptomatic severe aortic stenosis.
  • Uncontrolled symptomatic heart failure.
  • Inability to perform exercise Orthopedic impairment severely compromising exercise performance.
05

Study design

Phase
Not applicable
Primary purpose
Diagnostic
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
1,000 participants (estimated)

Study arms

  • Experimental
    Exercise Test

    maximal and anaerobic threshold cardiopulmonary parameters

    Diagnostic Test: Maximal exercise test

Interventions

  • Diagnostic testMaximal exercise test

    Each participants will conduct a spirometry test and exercise test on treadmill (using Modified Bruce Protocol) or cycle ergometer. Quark CPET metabolic cart (Cosmed, Rome, Italy) will be used to collect and analysis gas exchange, ECG, gas volume in addition rating of perceived exertion will be asked.

06

What researchers measure

Primary outcomes

  1. Maximal Oxygen consumption

    the maximum amount of oxygen that an individual can utilize during intense or maximal exercise.

    Time frame: through study completion, an average of 1 year

  2. Maximal Heart rate

    the maximum heart rate achieved during intense or maximal exercise.

    Time frame: through study completion, an average of 1 year

  3. Maximal Blood pressure

    the blood pressure in the end of intense or maximal exercise.

    Time frame: through study completion, an average of 1 year

Secondary outcomes

  1. Ventilation Anaerobic Threshold

    Ventilatory Threshold (VT) describes the inflection point for ventilation during an incremental exercise test.

    Time frame: through study completion, an average of 1 year

07

Study locations

1 of 1 sites recruiting
  • The BARUCH PADEH Medical Center, Poriya
    Tiberias, The Lower Galilee 15208, Israel
    Recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 21, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05263687
Lead sponsor
The Baruch Padeh Medical Center, Poriya
Responsible party
Gur Mainzer (Head of the pediatric cardiology department, The Baruch Padeh Medical Center, Poriya) — Principal investigator
First posted
Mar 2, 2022
Start date
Aug 30, 2017
Primary completion
Mar 19, 2025 (estimated)
Completion
Dec 30, 2025 (estimated)
Last update
Mar 21, 2022

Study contacts

Gur Mainzer, MD
Contact
GMainzer@poria.health.gov.il
+972543078940
Einat Kodesh, PhD
Contact
Ekodesh@poria.health.gov.il
+972523489854
Gur Mainzer, MD
principal investigator · The Baruch Padeh Medical Center, Poriya

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Mar 2022. You cannot join it, but the record below documents what was studied.

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