CClinicalTrials.gg
Status unknownNCT05262127Flash-EMDRUpdated Jan 4, 2023

Clinical Assessment of the Flash - Eye Movement Desensitization and Reprocessing

An interventional study of Flash Version of EMDR in PTSD, sponsored by York University. Status unknown at 2 sites in Canada. Open to participants aged 20 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-01-04.

Sponsored by York University · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Feb 2022), so the status shown — last known as Recruiting — may be out of date.

From the registry’s dates

  • Registered 3 months after the study started (first participant enrolled Sep 2021, registered Dec 2021).
Phase
Not applicable
Study type
Interventional
Enrollment
90
Allocation
Randomized
Ages
20 Years to 60 Years
Sex
All
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Study summary

To assess the Flash version of EMDR in reductions of the disturbance of upsetting memories at post-intervention, and 1-month follow up within a double-blinded, online 2-arm randomized controlled trial (RCT) with self-report outcomes. We will assess 45 per group, adequate for the detection of a medium effect size.

This double-blinded, RCT will assess the comparative efficacy of these two online interventions designed to reduce memory disturbance.

Read the detailed description

This double-blinded, RCT compares the efficacy of 2 online interventions (Flash Version - EMDR; EMDR alone) designed to reduce memory disturbance.Inclusion Criteria: (1) approved for engagement assessment by the CloudResearch platform; (2) 25-60 years; 3) US-Canada residence; (4) a recalled disturbing memory of an event that has not repeated and was moderately upsetting, or greater when event occurred; (5) memory remains moderately upsetting or greater on recall. The disturbance of upsetting memories at post-intervention, and 1-month follow up will be assessed with self-report outcomes. We will assess 45 / group, adequate for the detection of a medium effect size. linked to an earlier memory (that is equally or more disturbing). Exclusion Criteria: Diagnosis of: (1) bipolar disorder; (2) borderline personality disorder; (3) obsessive compulsive disorder; (4) schizophrenia; (5) substance abuse/addiction in the past 3 months; (6) any suicidal ideation; (7) suicide attempt in the past 6 months. Interventions: Experimental participants observe video instructions of full FT, while controls receive an online intervention that follows traditional EMDR. Measures: Primary outcome: State Anxiety subscale of the State Trait Anxiety Inventory (STAI) at baseline, post-intervention, and after 1-month follow up; Post Traumatic Stress Disorder symptoms (PTSD) measured by PCL-5 (1 month follow up).

Secondary outcomes: the Subjective Units of Disturbance (SUDs) assessing change in immediately reported disturbance of recalled memories (baseline and post-intervention); depression measured by Patient Health Questionnaire (PHQ9) and Positive-Negative Affect measured by the Positive and Negative Affect Scale (PANAS).

02

Conditions studied

  • PTSD

Keywords

  • behavioural internet intervention, post-traumatic stress
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In context

Lead sponsor

York University is the lead sponsor of 51 studies on the registry; 12 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Moderately upsetting or > memory of an event that occurred > 2 years ago and has since not repeated
  • Moderately upsetting or > memory remains moderately upsetting when recalled
  • Memory is not tied to an earlier memory that is equally disturbing or >

Exclusion criteria

Exclusion Criteria:

  • Bipolar Disorder
  • Borderline Personality Disorder
  • Obsessive-Compulsive Disorder
  • Schizophrenia
  • Substance Abuse/Addiction in past 3 months
  • Suicidal ideation or attempted suicide in the past 6 months
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Triple (Participant, Care provider, Outcomes assessor)
Enrollment
90 participants (estimated)

Study arms

  • Active comparator
    Flash Version of EMDR

    Flash methods (e.g. positive engaging focus) are used in addition to the standard EMDR techniques conveyed by video viewed online

    Behavioral: Flash Version of EMDR

  • Active comparator
    EMDR - alone

    Use of standard EMDR techniques conveyed by video online

    Behavioral: Flash Version of EMDR

Interventions

  • BehavioralFlash Version of EMDR

    EMDR and the inclusion of a positive engaging focus generated autonomously by participant

06

What researchers measure

Primary outcomes

  1. PTSD Checklist for DSM-5 (PCL-5) 1 - 44

    Self Report Questionnaire

    Time frame: 1 month follow up

  2. State-Trait Anxiety Inventory - State 0 - 80.

    Self Report Questionnaire

    Time frame: 1 month follow up

Secondary outcomes

  1. Patient Health Questionnaire 0 - 27

    Self Report Questionnaire

    Time frame: 1 month follow up

  2. Positive and Negative Affect Schedule 20 - 100

    Self Report Questionnaire

    Time frame: 1 month followup

07

Study locations

2 of 2 sites recruiting
  • York University
    Toronto, Ontario M3J 1P3, Canada
    • Paul Ritvo, PhD · Principal investigator
    Recruiting
  • York University - School of Kinesiology and Health Science
    Toronto, Ontario M4E 3C1, Canada
    Recruiting
08

References and documents

Individual participant data

Plan to share: Yes — Upon request, an anonymized data sheet (excel) will be sent

Supporting information: Study protocol, Sap, Icf, Csr

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 4, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05262127
Lead sponsor
York University
Responsible party
Paul Ritvo (Professor Kinesiology and Health Science, York University) — Principal investigator
First posted
Mar 2, 2022
Start date
Sep 1, 2021
Primary completion
Mar 1, 2023 (estimated)
Completion
Mar 1, 2023 (estimated)
Last update
Jan 4, 2023

Study contacts

Paul Ritvo, PhD
Contact
pritvo@yorku.ca
4165808021
Nazanin Babaei, BSc
Contact
nazaninb@my.yorku.ca
4167362100 ext. 22396

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Feb 2022. You cannot join it, but the record below documents what was studied.

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