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CompletedNCT05260554Updated Mar 2, 2022

Effect of Cranberry Extract on the Urinary System

An observational study in Urinary Tract Disease, Cystitis and Antibiotic Reaction, sponsored by Kırklareli University. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2022-03-02.

Sponsored by Kırklareli University · Observational

Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
2
Ages
18 Years and older
Sex
All
01

Study summary

In this study, we will try to emphasize the effects of using cranberry tablets, which is an alternative to antibiotic therapy, during uncomplicated urinary tract infections (only urinary tract, bladder and kidney infections did not).

Read the detailed description

This study was Istanbul Kartal Dr. Lütfi Kırdar Training and Research Hospital Emergency Medicine Clinic and Kırklareli Training and Research Hospital Emergency Service and Internal Medicine Polyclinic. Our study; includes patients who applied to the Emergency Department and Internal Medicine outpatient clinic with the complaint of dysuria and had normal WBC, CRP, urea, and creatinine values in their analysis, and leukocyturia was found in the urine test. Two options were offered in the treatment to these patients. Vaccinium Macrocarpon Aiton preparation or fosfomycin was given for seven days. The patients were asked whether their complaints had decreased according to the Lykert-Type verbal scale at the time of admission and on the first, third, and seventh days. When the treatment was finished, leukocytes were checked in the urinalysis. This outcome was compared between the 2 treatment options. We also noted whether nausea.

02

Conditions studied

  • Urinary Tract Disease
  • Cystitis
  • Antibiotic Reaction

Keywords

  • Urinary Tract Disease
  • Cranberry extract
  • Antibiotic
  • Cystitis
03

In context

Urologic Diseases

197 studies on the registry are indexed under Urologic Diseases; 49 are open to participants now.

This study's enrollment of 2 is below the median of 200 across 50 observational studies indexed under Urologic Diseases.

Browse Urologic Diseases studies →

Lead sponsor

Kırklareli University is the lead sponsor of 49 studies on the registry; 14 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Among the patients who were eligible criteria, the study was terminated when the number of patients in both groups reached 80.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Older than 18
  • who have urinary tract inflammation
  • who haven't kidney dissease previous

Exclusion criteria

Exclusion Criteria:

  • Younger than 18
  • Who have kidney inflammation
  • Pregnant patients
  • Who have blood test abnormal (WBC, Ure, Creatin, CRP high level)
05

Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
2 participants (actual)
Patient registry
No

Groups and cohorts

  • using fosfomycin

    The patients in this group; have been prescribed fosfomycin for 7 days (3 doses, two days apart).

    Drug: Fosfomycin

  • using cranberry extract

    The patients in this group; took 7 days (1 tablet each day) of cranberry tablets.

    Dietary Supplement: Cranberry

Interventions

  • In this group with urinary tract inflammation; Fosfomycin was prescribed for 7 days (3 doses, 2 days apart). There are 80 patients in total.

    Also known as: monurol

  • Dietary supplementCranberry

    In this group with urinary tract inflammation; 7 days (used every day) cranberry tablet was given. There are 80 patients in total.

06

What researchers measure

Primary outcomes

  1. Treatment time

    After 7 days of treatment, the 2 treatment options were compared with each other.

    Time frame: 7 days

07

Study locations

1 site
  • Oya Guven, MD
    Kırklareli, Center 39000, Turkey (Türkiye)
08

References and documents

Publications

  • Gray M. Are cranberry juice or cranberry products effective in the prevention or management of urinary tract infection? J Wound Ostomy Continence Nurs. 2002 May;29(3):122-6. doi: 10.1067/mjw.2002.124016. No abstract available. PubMed 12011903 ↗

Individual participant data

Plan to share: No — The data results of the patients will be described in the article.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 2, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05260554
Lead sponsor
Kırklareli University
Responsible party
Oya Guven, MD (Assistant Professor, Kırklareli University) — Principal investigator
First posted
Mar 2, 2022
Start date
Jan 26, 2022
Primary completion
Feb 18, 2022
Completion
Feb 18, 2022
Last update
Mar 2, 2022

Study contacts

Oya Guven
study director · Kırklareli University

Oversight

Data monitoring committee
No
FDA-regulated drug
Yes
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2022. You cannot join it, but the record below documents what was studied.

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