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CompletedNCT05250492APIUpdated Jul 16, 2026

Evaluation of Analgesia by PENG Block Versus Intra-Articular Infiltration in Prosthetic Hip Surgery (API)

An interventional study of Prosthetic hip surgery in Hip Prosthesis, Analgesia and PENG Block, sponsored by GCS Ramsay Santé pour l'Enseignement et la Recherche. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-07-16.

Sponsored by GCS Ramsay Santé pour l'Enseignement et la Recherche · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
60
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

The main objective of this study is to compare the effectiveness of the ultrasound-guided PENG block technique compared to intra-articular infiltration on postoperative morphine consumption during hip prosthetic surgery via the anterior minimally invasive approach under general anesthesia.

02

Conditions studied

  • Hip Prosthesis
  • Analgesia
  • PENG Block

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03

In context

Agnosia

1,190 studies on the registry are indexed under Agnosia; 508 are open to participants now.

This study's enrollment of 60 is below the median of 78 across 1,024 interventional studies indexed under Agnosia.

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Lead sponsor

GCS Ramsay Santé pour l'Enseignement et la Recherche is the lead sponsor of 198 studies on the registry; 94 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Patient, male or female, over 18 years old.
  • Patient scheduled for anterior hip prosthesis.
  • Affiliated patient or beneficiary of a social security scheme.
  • Patient having been informed and having signed a free and informed consent.

Exclusion criteria

Exclusion Criteria:

  • Patient with a contraindication to local anesthesia.
  • Patient with a high level of dependence, defined by level 1 or 2 of the Iso-Ressources Group (GIR).
  • Patient participating in another clinical study.
  • Protected patient: adult under guardianship, curatorship or other legal protection, deprived of freedom by judicial or administrative decision.
  • Pregnant, breastfeeding or parturient woman.
  • Patient hospitalized without consent.
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
60 participants (actual)

Study arms

  • Experimental
    Patients with PENG block

    Procedure: Prosthetic hip surgery

  • Active comparator
    Patients with intra-articular infiltration

    Procedure: Prosthetic hip surgery

Interventions

  • ProcedureProsthetic hip surgery

    Total hip prosthesis performed by an anterior approach with intra-articular infiltration of an anesthetic product intraoperatively. OR \- Total hip prosthesis performed by an anterior approach with infiltration of the same anesthetic product by ultrasound-guided PENG block intraoperatively.

06

What researchers measure

Primary outcomes

  1. Postoperative morphine consumption in the postoperative care unit

    Postoperative morphine consumption (in mg) in the postoperative care unit

    Time frame: 1 hour

Secondary outcomes

  1. Postoperative morphine équivalent consumption at postoperative day 1

    postoperative morphine équivalent consumption (in mg) at postoperative day 1

    Time frame: 1 day

07

Study locations

1 site
  • Jean-François Oudet
    Lanester, 56600, France
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 16, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT05250492
Lead sponsor
GCS Ramsay Santé pour l'Enseignement et la Recherche
Collaborators
European Clinical Trial Experts Network
Responsible party
Sponsor
First posted
Feb 22, 2022
Start date
Mar 2, 2022
Primary completion
Sep 9, 2022
Completion
May 15, 2023
Last update
Jul 16, 2026

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.

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