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CompletedNCT05221983Updated Feb 21, 2022

COVID-19 and Vitamin D: Length of Hospital Stay and Mortality

An observational study in COVID-19 Pandemic and Vitamin D Deficiency, sponsored by Yuksek Ihtisas University. Completed at 1 site in Turkey. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2022-02-21.

Sponsored by Yuksek Ihtisas University · Observational

Study type
Observational
Model
Case-only
Time perspective
Retrospective
Enrollment
168
Ages
18 Years and older
Sex
All
01

Study summary

The lack of a pharmacological treatment in the COVID-19 pandemic has pushed scientists to search for this issue. Maintaining optimal health is parallel to adequate and balanced nutrition. In this context, can the protective properties of vitamin D play an important role in this pandemic? brought with it the thought. In this study, it was aimed to examine the effect of vitamin D on mortality and hospital stay in COVID-19 disease.

Read the detailed description

This research was conducted to examine the effect of vitamin D on mortality and hospital stay in COVID-19 disease. For this, the approval of the Ministry of Health and then the ethics committee was obtained. For this reason, patients with positive PCR tests and hospitalized patients with vitamin D levels in their biochemistry were included in the study.

The data of the patients were obtained from the medical records. Information such as age, gender, comorbidities, length of hospital stay, vitamin D level were included in the study. According to the statistical analyzes obtained from these data, it has been shown that vitamin D level has no effect on mortality and hospital stay in COVID-19 disease.

02

Conditions studied

  • COVID-19 Pandemic
  • Vitamin D Deficiency

Keywords

  • COVID-19
  • Vitamin D
  • Length of stay
  • Mortality
03

In context

COVID-19

7,640 studies on the registry are indexed under COVID-19; 488 are open to participants now.

This study's enrollment of 168 is below the median of 261 across 3,136 observational studies indexed under COVID-19.

Browse COVID-19 studies →

Lead sponsor

Yuksek Ihtisas University is the lead sponsor of 21 studies on the registry; 3 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Adult patients with positive COVID-19 PCR (Polymerase Chain Reaction) test and vitamin D level in biochemical parameters, who applied to Ankara City Hospital Neurology-Orthopedics Hospital between 01 August and 31 October 2020.

Inclusion criteria

  • COVID-19 PCR (Polymerase Chain Reaction) test positive
  • Vitamin D level in biochemical parameters
  • Adult patients hospitalized for COVID-19

Exclusion criteria

Exclusion Criteria:

-Patients using drugs that may affect vitamin D absorption, such as corticosteroids, cholesterol-lowering agents, phenobarbital and phenytoin-containing agents

05

Study design

Observational model
Case-only
Time perspective
Retrospective
Enrollment
168 participants (actual)
Patient registry
No

Groups and cohorts

  • Patients with COVID-19 + with vitamin D levels

    Patients with COVID-19 + and vitamin D levels were included in the study retrospectively. Vitamin D level was categorized into 3 groups as inadequacy, deficiency and normal from medical records. No intervention was made.

06

What researchers measure

Primary outcomes

  1. Level of Vitamin D

    Vitamin D levels of patients with a diagnosis of COVID-10. These results were categorized at the level of deficiency/insufficiency/normal.

    Time frame: 1 month later

  2. Relationship between vitamin D level and mortality

    Relationship between survival and death by categorized vitamin D level.

    Time frame: 1 month later

  3. Relationship between vitamin D level and hospital stay

    Length of hospital stay by categorized vitamin D level.

    Time frame: 1 month later

Secondary outcomes

  1. Effects of additional diseases (Diabetes mellitus, hypertension, etc.) on hospital stay and mortality

    Evaluation of the impact of comorbidities on survival during COVID-19 disease.

    Time frame: 1 month later.

07

Study locations

1 site
  • Republic of Turkey Ministry of Health Ankara City Hospitals Neurology-Orthopedics Hospital
    Ankara, 06800, Turkey
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 21, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05221983
Lead sponsor
Yuksek Ihtisas University
Collaborators
Ankara City Hospital Bilkent
Responsible party
Sevan ÇETİN ÖZBEK (Assistant Professor, Yuksek Ihtisas University) — Principal investigator
First posted
Feb 3, 2022
Start date
Aug 21, 2021
Primary completion
Nov 9, 2021
Completion
Nov 16, 2021
Last update
Feb 21, 2022

Study contacts

Levent Öztürk, MD
study director · Republic of Turkey Ministry of Health Ankara City Hospitals Neurology-Orthopedics Hospital

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2022. You cannot join it, but the record below documents what was studied.

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