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CompletedNCT05192733PRICE1Updated Mar 22, 2022

PRICE Survey Of Extubation Following Infratentorial Craniotomy

An observational study in Infratentorial Neoplasms, sponsored by Centre Hospitalier Universitaire Vaudois. Completed at 1 site in Switzerland. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2022-03-22.

Sponsored by Centre Hospitalier Universitaire Vaudois · Observational

Study type
Observational
Model
Other
Time perspective
Cross-sectional
Enrollment
190
Ages
18 Years and older
Sex
All
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Study summary

The PRICE study primarily aims to identify predictors of early extubation following elective infratentorial craniotomy in adults. It also aims to (i) measure the rate of early extubation in different clinical settings; and (ii) study how the decision to extubate early is made and communicated in clinical practice. The first phase of the study (PRICE1) is a brief online survey addressed to physicians in charge of neurosurgical patients (neuroanesthesiologists, neurosurgeons, neurocritical care specialists) in multiple countries.

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Conditions studied

  • Infratentorial Neoplasms

Keywords

  • Airway Extubation
  • Prediction
  • Prevalence
  • Survey
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In context

Infratentorial Neoplasms

21 studies on the registry are indexed under Infratentorial Neoplasms; 5 are open to participants now.

Browse Infratentorial Neoplasms studies →

Lead sponsor

Centre Hospitalier Universitaire Vaudois is the lead sponsor of 208 studies on the registry; 47 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Sampling method
Non-probability sample

Study population

Physicians involved in delivering care to neurosurgical patients: neuroanesthesiologists, neurosurgeons, neurocritical care specialists

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Physician actively involved in delivering care to neurosurgical patients
  • Physician formerly involved in delivering care to neurosurgical patients

Exclusion criteria

Exclusion Criteria:

  • Has already completed the survey
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Study design

Observational model
Other
Time perspective
Cross-sectional
Enrollment
190 participants (actual)
Patient registry
No

Groups and cohorts

  • Clinical Specialty

    We will compare responses across the following clinical specialties : 1. Neuroanesthesiologists 2. Neurosurgeons 3. Neurocritical care specialists NB: Some participants may have a double clinical specialty.

    Other: Survey

  • Clinical Setting

    We will compare responses across the following clinical settings: 1. Cities 2. Countries 3. Number of cases per year

    Other: Survey

Interventions

  • OtherSurvey

    This is a cross-sectional practice survey. There is no intervention.

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What researchers measure

Primary outcomes

  1. Prevalence of early extubation

    Percentage of patients being extubated early, as estimated by responders. Early extubation is defined as extubation at the end of surgery, in the operating room, prior to discharge to recovery or intensive care.

    Time frame: 3 months

Secondary outcomes

  1. Inventory of perceived main predictors of early extubation

    Participants to the survey can select up to 3 of the following options: Survey options are: Patient's level of consciousness Evidence of brainstem dysfunction Patient's physical status prior to surgery History or suspicion of difficult airway Preoperative imaging Duration of surgery Course of surgery Time of day when surgery ends Other (to be completed by responder)

    Time frame: 3 months

  2. Personnel perceived to make the decision to extubate early

    Participants to the survey can select 1 or several of the following options: Anesthesiologist Neurosurgeon Neurocritical care physician

    Time frame: 3 months

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Study locations

1 site
  • Centre Hospitalier Universitaire Vaudois
    Lausanne, Canton of Vaud 1011, Switzerland
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References and documents

Publications

  • Cata JP, Saager L, Kurz A, Avitsian R. Successful extubation in the operating room after infratentorial craniotomy: the Cleveland Clinic experience. J Neurosurg Anesthesiol. 2011 Jan;23(1):25-9. doi: 10.1097/ANA.0b013e3181eee548. PubMed 21252705 ↗
  • Cai YH, Wang HT, Zhou JX. Perioperative Predictors of Extubation Failure and the Effect on Clinical Outcome After Infratentorial Craniotomy. Med Sci Monit. 2016 Jul 12;22:2431-8. doi: 10.12659/msm.899780. PubMed 27404044 ↗
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Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Ran from Nov 2021 to primary completion in Feb 2022, 3 months.

How these figures are worked out, and which studies are left out of them.

Registered
Dec 13, 2021
First posted
Jan 14, 2022
StartActual
Nov 4, 2021
Primary completionActual
Feb 15, 2022
CompletionActual
Feb 15, 2022
Last update
Mar 22, 2022
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Mar 22, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05192733
Collaborators
Hervé Quintard, Torstein Meling, Nicolai Goettel, Lien Jakus, Camille Levy
Responsible party
John Gaudet (Chef de Clinique en Anesthésie, Centre Hospitalier Universitaire Vaudois) — Principal investigator
First posted
Jan 14, 2022
Start date
Nov 4, 2021
Primary completion
Feb 15, 2022
Completion
Feb 15, 2022
Last update
Mar 22, 2022

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2022. You cannot join it, but the record below documents what was studied.

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