An interventional study of inclusion and familiarization and fMRI acquisition and closure in Magnetic Resonance Imaging and Neuronal Activity, sponsored by Centre Hospitalier Universitaire de Saint Etienne. Completed at 2 sites in France. Open to participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-08-04.
Sponsored by Centre Hospitalier Universitaire de Saint Etienne · Not applicable, Interventional, and Basic science
Understanding babies' signals is essential to meet their needs. Recent works suggest that crying provides useful information, not only allowing parents to recognize their baby among others (static information), but also to distinguish between mild discomfort and pain cries (dynamic information). The perception of this information by adults involves a "parental" brain network including brain areas involved in empathy, attention, emotional regulation, motor as well as regions of the limbic system or associated with the reward network.
This network is involved when listening to cries of familiar babies, or pain cries. How do we become specialist of a baby's cries? To date, no functional imaging study has examined the specific brain activations when listening to the cries of a familiar baby in different situations, particularly painful ones.
Centre Hospitalier Universitaire de Saint Etienne is the lead sponsor of 578 studies on the registry; 128 are open to participants now.
Counted across the registry records on this site, refreshed daily.
For all volunteers:
Group with parental experience caring for infants :
Group with professional experience in caring for infants
Exclusion Criteria
Women parent of a child under 2 years old
Behavioral: inclusion and familiarization · Behavioral: fMRI acquisition and closure
Men parent of a child under 2 years old
Behavioral: inclusion and familiarization · Behavioral: fMRI acquisition and closure
Women in daily contact with infants in professional circle (e.g., nannies, pediatricians, midwives, maternity nurses) without dependent children under 2 years old
Behavioral: inclusion and familiarization · Behavioral: fMRI acquisition and closure
* presentation of the study purpose and the protocol to the volunteer * clinical examination to check inclusion and exclusion criteria * Familiarization with the crying of one assigned baby, by listening to several bath cries from this baby
* Second phase of familiarization, listening again to bath cries of "their" assigned baby. These cries will be different from those listened during the first familiarization phase. * MRI acquisition: after acquisition of the anatomical images (5 min), the subjects will listen to 64 cries divided into 4 functional MRI sessions of 10 minutes each. The cries will be those of "their" baby or of unknown babies, evoked in a painful (vaccination) or a non-painful (bath) situation, presented in a pseudo-random order. Participants will be asked to assess whether they recognize "their" baby (yes/no) and whether they recognize a pain cry (yes/no). * debriefing * Protocol ending
BOLD signal (blood oxygen level-dependent)
Measurement of the BOLD signal by fMRI (functional magnetic resonance imaging) in adults during listening to natural cries of a familiar baby and unknown babies, in two painful (vaccination) or non-painful (bath) situations.
Time frame: during the whole listening session
participants'experience at caring for babies
Experience at caring for babies : Yes or No
Time frame: At the inclusion visit
participants' sex
Sex : Male or female
Time frame: At the inclusion visit
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Jun 2023. You cannot join it, but the record below documents what was studied.
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Centre Hospitalier Universitaire de Saint Etienne