An observational study in Athlete Heart, sponsored by Universitaire Ziekenhuizen KU Leuven. Recruiting at 4 sites in 2 countries. Open to participants aged 14 Years to 23 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-12-20.
Sponsored by Universitaire Ziekenhuizen KU Leuven · Observational
The Pro@Heart (Prospective Athlete's Heart) study is an international multicentre long-term prospective trial. The primary objective of the Pro@Heart study is to investigate the impact of training load (i.e. accurately evaluated in term of type, frequency, duration and intensity) and genotype on the variability of structural, functional and electrical exercise induced cardiac remodeling (EICR) in young competitive endurance athletes. The second objective is to determine how EICR, training load and genotype are associated with physical performance, health benefits and cardiac pathology (e.g. exercise-related cardiomyopathies and arrhythmias) during follow-up over several decades.
Universitaire Ziekenhuizen KU Leuven is the lead sponsor of 928 studies on the registry; 261 are open to participants now.
Of its 5 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
Athletes aged 14 to 23 years recruited from elite endurance sports programs and organisations including Cycling Vlaanderen, Triatlon Vlaanderen, Belgian Cycling, Cycling Australia, Rowing Australia and Athletics Australia and from sports performance centres including Nottebohm Antwerpen, Bakala Academy Leuven and Adlon Hasselt. Volunteers recruited by means of 'word of mouth' and social media campaigns within elite endurance sporting circles. Non-athletes consist of age and gender matched university and college students recruited from Australian and Belgian universities in addition to social media campaigns.
Athletes competing in endurance sports at national or international level for at least 2 years. Sports include:
Exclusion Criteria:
1. Males and females aged 14-23 years old 2. Athletes competing in endurance sports at national or international level for at least 2 years. Sports include: 1. Triathlon 2. Cycling 3. Distance running (≥ 1500 meters) 4. Rowing 5. Swimming
Other: No intervention
1. Males and females aged 14-23 years old 2. Non athletes engaged in \< 3 hours per week of physical activity
Other: No intervention
No intervention
Genotype
Rare and common variants in cardiomyopathy associated genes
Time frame: Baseline
Training load
Duration and intensity of training
Time frame: Baseline to 20 years
Atrial fibrillation
Time frame: Baseline to 20 years
Ventricular arrhythmias
Ventricular ectopic beats, non-sustained and sustained ventricular tachycardia
Time frame: Baseline to 20 years
Plan to share: Undecided
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Universitaire Ziekenhuizen KU Leuven