An interventional study of Tai-Chi and Comprehensive training in Sarcopenia in Elderly and Tai Chi, sponsored by China Medical University Hospital. Completed at 1 site in Taiwan. Open to participants aged 60 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-01-19.
Sponsored by China Medical University Hospital · Not applicable, Interventional, and Health services research
Sarcopenia has been defined as a disease which presented as low muscles strength, low muscle quantity or quality and low physical activity. The prevalence of sarcopenia is increasing with the age and it is also included in one of geriatric syndromes. Several criteria have been mentioned for diagnosis of sarcopenia, such as European Working Group on Sarcopenia in Older People (EWGSOP)、Foundation for the National Institutes of Health Biomarkers Consortium Sarcopenia Project (FNIH) and Asian Working Group for Sarcopenia (AWGS).
In European, the prevalence rate of sarcopenia is 9.25-18%; 5-7% Canadian and 14.4% Taiwanese elders have been diagnosed as sarcopenia, respectively. The sarcopenia has been found its relationship with adverse outcomes of fall down, fracture, disability, and death. The cytokines and decline in anabolic hormones play a role in the pathogenesis of sarcopenia. Tai Chi exercise is one of Qigong and well-popular in Chinese population, and is helpful to integration of body movements. Tai Chi exercise is less complicated and emphasized people's awareness of self-care which presented the relationship between human and nature. Tai Chi exercise could improve muscle performance, balance and have the benefit for fall down prevention in the elders and patients with frailty. Furthermore, Tai Chi has been found that it also could improve the muscle power and power strength in sarcopenic elders by team training. Furthermore, immune makers of inflammation process have been noted their diminishments by Qigong intervention.
The aim of this study is to investigate the effect of Tai Chi exercise in sarcopenic elders through practicing at home. The differences of muscles strength, muscle quantity or quality and physical activity after interventions would be recorded and analyzed. The cytokines related to the sarcopenia process would also be sampled.
1,208 studies on the registry are indexed under Sarcopenia; 402 are open to participants now.
This study's enrollment of 60 is close to the median of 60 across 775 interventional studies indexed under Sarcopenia.
Browse Sarcopenia studies →China Medical University Hospital is the lead sponsor of 464 studies on the registry; 116 are open to participants now.
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Exclusion Criteria:
In addition to standard of care participants will be asked to apply Tai Chi. There are 8 movements. Each session consisted of 10 minutes of warm-up, 40 minutes of Tai Chi, and 10 minutes of cool down. The 8 movements are: Ward-off, Rollback, Push, Press, Grab, Split, Elbow strike, and shoulder strike.
Behavioral: Tai-Chi
In addition to standard of care participants will be asked to apply Comprehensive training. There are 3 exercises. Each session consisted of 10 minutes of warm-up, 40 minutes of Tai Chi, and 10 minutes of cool down. The 8 movements are: stretch exercise, strengthening exercise, and balance exercise.
Behavioral: Comprehensive training
Tai Chi exercise could improve muscle performance, balance and have the benefit for fall down prevention in the elders and patients with frailty.
Also known as: Ward-off, Rollback, Push, Press, Grab, Split, Elbow Strike, Shoulder Strike
There are 3 exercises. Each session consisted of 10 minutes of warm-up, 40 minutes of Tai Chi, and 10 minutes of cool down.
Also known as: Stretch exercise, Strengthening exercise, Balance training
Appendicular skeletal muscle mass in kilograms
The appendicular skeletal muscle mass is evaluated by bioelectrical impedance (BIA) analysis
Time frame: baseline
Change from baseline appendicular skeletal muscle mass at 8 weeks
The appendicular skeletal muscle mass is evaluated by bioelectrical impedance (BIA) analysis
Time frame: 8 weeks
Hand grip in kilograms
The muscle strength is evaluated with the hand-grip strength (kg) by dynamometer
Time frame: baseline
Hand grip in kilograms
The muscle strength is evaluated with the hand-grip strength (kg) by dynamometer
Time frame: 8 weeks
Times Chair-stand test (5-CST) in minutes
The 5CST is evaluated by recording the total time that patient repeat 5 times stand and sit motion from chair
Time frame: baseline
Times Chair-stand test (5-CST) in minutes
The 5CST is evaluated by recording the total time that patient repeat 5 times stand and sit motion from chair
Time frame: 8 weeks
This study is completed, as verified in Jan 2023. You cannot join it, but the record below documents what was studied.
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China Medical University Hospital