CClinicalTrials.gg
Enrolling by invitationNCT05112302Updated Jan 21, 2026

A Study to Evaluate Virtual Reality As Adjunct to Anesthesia During Orthopedic Surgery

An observational study in Knee Arthropathy and Hip Injuries, sponsored by Mayo Clinic. Enrolling by invitation at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-01-21.

Sponsored by Mayo Clinic · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
50
Ages
18 Years and older
Sex
All
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Study summary

The purpose of this study is to obtain feedback from patients and orthopedic surgeons who agree to use virtual reality (VR ) as an adjunct to standard of care in orthopedic cases under regional or central neuraxial nerve block. This will serve as a preliminary study for future trials to compare outcomes between VR and standard of care vs standard of care only.

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Conditions studied

  • Knee Arthropathy
  • Hip Injuries

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Keywords

  • virtual reality
  • knee arthroplasty
  • hip arthroplasty
03

In context

Hip Injuries

58 studies on the registry are indexed under Hip Injuries; 14 are open to participants now.

This study's planned enrollment of 50 is below the median of 82 across 18 observational studies indexed under Hip Injuries.

Browse Hip Injuries studies →

Lead sponsor

Mayo Clinic is the lead sponsor of 3,218 studies on the registry; 670 are open to participants now.

Of its 445 completed or terminated interventional studies of FDA-regulated products, 313 (70%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Adult patients undergoing elective orthopedic surgery

Inclusion criteria

  • Age ≥ 18 years old.
  • Patients scheduled for orthopedic procedure under regional or central neuraxial nerve block (anterior primary hip arthroplasty or primary knee arthroplasty).
  • Subject willing to participate and able to provide informed consent.

Exclusion criteria

Exclusion Criteria:

  • Age \< 18 years old.
  • History of motion sickness or blindness.
  • Unable to consent due to cognitive difficulty.
  • Current diagnosis of epilepsy, dementia, or other neurological disease that may prevent use of VR hardware and software.

Sensitivity to flashing light or motion.

  • Recent stroke.
  • Injury to the eyes, face, neck, or arms that prevents comfortable use of VR hardware or software, or safe use of the hardware (e.g., open wound, sores, or skin rash on face).
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
50 participants (estimated)
Patient registry
No

Groups and cohorts

  • Virtual reality

    Other: Virtual reality

Interventions

  • OtherVirtual reality

    Use of virtual reality goggles during procedure

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What researchers measure

Primary outcomes

  1. Impact of virtual reality on anxiety level

    Evaluate patients' satisfaction with using virutal reality and reduction in anxiety during orthopedic procedures

    Time frame: Up to 2 hours

Secondary outcomes

  1. Impact of virtual reality on pharmacological therapy doses

    Elucidate the impact of VR on pharmacological therapy doses required for proper analgesia and anxiolysis and on reduction of drug side effects in patient using VR during surgeries.

    Time frame: Up to 2 hours

  2. Impact of virtual reality on patient's perioperative temperature

    Evaluate if utilizing virtual reality has a positive impact in preventing patient hypothermia intra- and post-operatively.

    Time frame: Up to 3 hours

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Study locations

1 site
  • Mayo Clinic in Florida
    Jackson, Florida 32224, United States
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References and documents

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 21, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05112302
Lead sponsor
Mayo Clinic
Responsible party
Klaus D. Torp (Principal Investigator, Mayo Clinic) — Principal investigator
First posted
Nov 8, 2021
Start date
Aug 17, 2021
Primary completion
Dec 2026 (estimated)
Completion
Dec 2026 (estimated)
Last update
Jan 21, 2026

Study contacts

Klaus Torp, MD
principal investigator · Mayo Clinic

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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No contact was published for this record. The registry link below has the sponsor’s details.

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