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CompletedNCT05091983ODYSSEDUpdated Sep 12, 2025

Restrictive Eating Disorders: From Childhood Orality Disorder to Adolescent Dysensoriality

An observational study in Eating Disorders in Adolescence and Avoidant Restrictive Food Intake Disorder, sponsored by Assistance Publique - Hôpitaux de Paris. Completed at 1 site in France. Open to participants aged 12 Years to 18 Years. Per ClinicalTrials.gov, last updated 2025-09-12.

Sponsored by Assistance Publique - Hôpitaux de Paris · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
29
Ages
12 Years to 18 Years
Sex
All
01

Study summary

This study offers to determine whether adolescent patients with a restrictive eating disorder have variations in their sensoriality compared to a control group.

Read the detailed description

Eating disorders are a frequent reason for consultation in pediatrics at all ages.

When they are small, children may have an orality disorder. There are multiple potential causes for this disorder: psychogenic, oropraxic but also sensory. The treatment is then adapted to the patient, with, among other things, an orientation towards professionals trained in sensory disorders.

As they grow up, adolescents are particularly at risk of developing eating disorders, which are pathologies that correspond to a biopsychosocial model of understanding that includes psychogenetic, neuroendocrine and immune factors.

Despite major advances in the understanding of this disease, the sensory dimension for these patients is still little studied and is not taken into account in the treatment proposed to adolescents suffering from eating disorders.

02

Conditions studied

  • Eating Disorders in Adolescence
  • Avoidant Restrictive Food Intake Disorder

Keywords

  • Restrictive eating disorder
  • anorexia nervosa
  • Avoidant/Restrictive Food Intake Disorder
  • sensory modulation disorder
  • sensory modulation symptoms
  • sensory over responsivity
  • sensory integration
03

In context

Avoidant Restrictive Food Intake Disorder

35 studies on the registry are indexed under Avoidant Restrictive Food Intake Disorder; 12 are open to participants now.

This study's enrollment of 29 is below the median of 106 across 10 observational studies indexed under Avoidant Restrictive Food Intake Disorder.

Browse Avoidant Restrictive Food Intake Disorder studies →

Lead sponsor

Assistance Publique - Hôpitaux de Paris is the lead sponsor of 3,505 studies on the registry; 1,006 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
12 Years to 18 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

The participants were all recruited at the Maison de Solenn, Cochin - Paris, a service specialized in the treatment of eating disorders for adolescents. The participants in the control group are patients followed in this center for another reason than an eating disorder. The participants were recruited in consultation, in day hospital or in complete hospitalization.

Inclusion criteria

  • Adolescent between 12 to 18 years old.
  • Non-opposition of the adolescent and his or her legal guardians collected before the start of the study.
  • Patient group: Diagnosis of restrictive eating disorders (Anorexia Nervosa typical or atypical, ARFID) meeting DSM-5 criteria.
  • Control group: absence of eating disorders.

Exclusion criteria

Exclusion Criteria:

  • Eating disorders secondary to another psychiatric pathology.
  • Precarious health status with somatic and/or psychiatric instability that does not allow to answer the questionnaire.
  • Language barrier.
  • Opposition of the adolescent and/or his/her legal representatives obtained before the start of the study
  • Patient under " AME " (medical state help)
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
29 participants (actual)
Patient registry
No

Groups and cohorts

  • Restrictive eating disorder group

    Adolescents between 12 and 18 y.o. Restrictive eating disorders diagnosis (Anorexia Nervosa or ARFID) answering DSM-5 criteria

    Other: Sensory Processing Scale Inventory (SPSI) · Other: Autism Spectrum Screening Quotient (ASSQ) · Other: GAD 7 · Other: Conners abridged · Other: EAT 26

  • Control group

    Adolescents between 12 and 18 y.o. No eating disorders

    Other: Sensory Processing Scale Inventory (SPSI) · Other: Autism Spectrum Screening Quotient (ASSQ) · Other: GAD 7 · Other: Conners abridged

Interventions

  • OtherSensory Processing Scale Inventory (SPSI)

    The Sensory Processing Scale Inventory (SPSI) is the main questionnaire. It allows to define over and under sensitive profiles. It's a self-administrated questionnaire

  • OtherAutism Spectrum Screening Quotient (ASSQ)

    The ASSQ allows to detect autism spectrum disorders (ASD). This quotient is proposed to the group because the investigators know that ASD are often correlated with sensory integration disorders. It's answered by the participant's parents.

  • OtherGAD 7

    The GAD7 questionnaire allows to detect anxiety disorder. This questionnaire is proposed to the group because the investigators know that anxiety disorders are often correlated with sensory integration disorders. It's a self-administrated questionnaire.

  • OtherConners abridged

    The Conners abridged questionnaire allows to detect attention-deficit hyperactivity disorder (ADHD). This questionnaire is proposed to the group because the investigators know that ADHD are often correlated with sensory integration disorders. The questionnaire is answered by the participant's parents.

  • OtherEAT 26

    The EAT 26 questionnaire allows to detect anorexia nervosa. It is proposed to the patient with an eating disorder to establish the level of severity of their disease. It's a self-administrated questionnaire.

06

What researchers measure

Primary outcomes

  1. Average Sensory Processing Scale Inventory (SPSI) scores between the two groups

    Comparison of average Sensory Processing Scale Inventory (SPSI) scores between the two groups This questionnaire focuses on sensoriality. It allows the definition of over or under-reactive sensory profiles. It is made of two lists (list #1 : 73 items ; list #2 : 29 items). The SPSI questionnaire is in English. For this reason, a group of experts from La Maison de Solenn met to translate it into French being as faithful as possible to the original questionnaire. Each checklist has its own score, the result is the sum of the points obtained (one point for YES, zero points for NO) (6). Two groups will be formed: a group with eating disorders and a control group. The questionnaire will be answered only once and will be proposed to the participant at the end of a consultation at the Maison de Solenn for his usual follow-up or during a hospitalization (full time hospitalization or in day hospital).

    Time frame: Inclusion

Secondary outcomes

  1. Screening for pathologies known to be associated with a sensory disorder

    Screening questionnaires for Autism Spectrum Disorder (ASD) will be distributed in order to identify disorders associated with a particular sensory profile. This will allow statistical results to be refined by performing multivariate analyses.

    Time frame: Inclusion

  2. Screening for pathologies known to be associated with a sensory disorder

    Screening questionnaires for Attention Deficit Hyperactivity Disorder (ADHD) will be distributed in order to identify disorders associated with a particular sensory profile. This will allow statistical results to be refined by performing multivariate analyses.

    Time frame: Inclusion

  3. Screening for pathologies known to be associated with a sensory disorder

    Screening questionnaires for Generalized Anxiety Disorder (GAD) will be distributed in order to identify disorders associated with a particular sensory profile. This will allow statistical results to be refined by performing multivariate analyses.

    Time frame: Inclusion

  4. Search for a link between the eating disorders severity and sensory disorders

    The EAT 26 questionnaire is used to measure the severity of an eating disorder. It will be proposed only to the participants of the eating disorder group. This measure of severity will assess whether there is a relationship between the severity of the ED and the severity of the sensory disorders.

    Time frame: Inclusion

07

Study locations

1 site
  • Maison de Solenn Maison des Adolescents, Cochin Hospital
    Paris, IDF 75014, France
08

References and documents

Publications

  • Battle DE. Diagnostic and Statistical Manual of Mental Disorders (DSM). Codas. 2013;25(2):191-2. doi: 10.1590/s2317-17822013000200017. No abstract available. PubMed 24413388 ↗
  • Gorwood P, Blanchet-Collet C, Chartrel N, Duclos J, Dechelotte P, Hanachi M, Fetissov S, Godart N, Melchior JC, Ramoz N, Rovere-Jovene C, Tolle V, Viltart O, Epelbaum J. New Insights in Anorexia Nervosa. Front Neurosci. 2016 Jun 29;10:256. doi: 10.3389/fnins.2016.00256. eCollection 2016. PubMed 27445651 ↗
  • Schoen SA, Miller LJ, Green KE. Pilot study of the Sensory Over-Responsivity Scales: assessment and inventory. Am J Occup Ther. 2008 Jul-Aug;62(4):393-406. doi: 10.5014/ajot.62.4.393. PubMed 18712002 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 12, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05091983
Lead sponsor
Assistance Publique - Hôpitaux de Paris
Collaborators
URC-CIC Paris Descartes Necker Cochin
Responsible party
Sponsor
First posted
Oct 25, 2021
Start date
Nov 30, 2021
Primary completion
Mar 24, 2022
Completion
Mar 24, 2022
Last update
Sep 12, 2025

Study contacts

Corinne BLANCHET
principal investigator · APHP - Cochin Hospital

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Sep 2025. You cannot join it, but the record below documents what was studied.

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