An interventional study of Exercise in Healthy, Athlete and Performance, sponsored by University of Salzburg. Completed at 1 site in Austria. Open to participants aged 18 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-01-31.
Sponsored by University of Salzburg · Not applicable, Interventional, and Treatment
A randomized, controlled trial to evaluate the effects of two versions of 10 high intensity interval trainings (HIIT) within a 7-day shock microcycle on endurance performance, well-being, health, stress and recovery in trained athletes.
Thirty-six trained endurance athletes will be recruited and randomly assigned to either a "high volume (HIIT-HV)" group, a "low volume (HIIT-LV)" group, or a control group. All participants will be monitored before (9 days), during (7 days), and after (14 days) a 7-day training intervention, for 30 days. Participants in both intervention groups will complete 10 HIIT sessions within the period of 7 days, with an additional 30 minutes of low-intensity training exclusively in HIIT-HV. HIIT sessions consist of aerobic HIIT, i.e., 5x4min at 90-95% of maximal heart rate interspersed by 2.5 min active recovery periods. To determine the effects of the intervention, performance diagnostics, and a 5 kilometer time trial will be conducted before and after the intervention. In addition, participants are closely monitored for general health, stress, fatigue, recovery, neuromuscular performance, executive functions and sleep.
University of Salzburg is the lead sponsor of 11 studies on the registry; 1 is open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
HIIT-HV - high intensity interval training high volume Participants complete a total of 10 HIIT sessions over a 7-day period consisting of 5 x 4-minute intervals at an intensity of 90-95% of their individual maximum heart rate (HRmax), interspersed with a 2.5-minute active recovery period. Each training session is followed by 30 minutes of low-intensity training (total of 300 minutes of additional low-intensity training during this period).
Other: Exercise
HIIT- LV - high intensity interval training low volume Participants complete a total of 10 HIIT sessions over a 7-day period consisting of 5 x 4-minute intervals at an intensity of 90-95% of their individual maximum heart rate (HRmax), interspersed with a 2.5-minute active recovery period.
Other: Exercise
Participants continue with their regular training program.
high-intensity interval training sessions
Endurance performance I
Change of maximal oxygen uptake (VO2max in ml/min/kg) compared to baseline and group
Time frame: 10 to 21 days (assessment is conducted once before the intervention and repeated three times afterwards, i.e. 3, 7 and 14 days after the completion of the intervention)
Endurance performance II
Change of peak performance (Ppeak in Watt) compared to baseline and group
Time frame: 10 to 21 days (assessment is conducted once before the intervention and repeated three times afterwards, i.e. 3, 7 and 14 days after the completion of the intervention)
Endurance performance III
Change of 5 kilometer time trial performance (in sec) compared to baseline and group
Time frame: 20 to 22 days (the assessment is conducted once before, and once after the intervention)
Endurance performance IV
Change of lactate threshold (in km/h) compared to baseline and group
Time frame: 10 to 21 days (assessment is conducted once before the intervention and repeated three times afterwards, i.e. 3, 7 and 14 days after the completion of the intervention)
Endurance performance V
Change of ventilatory thresholds (in km/h) compared to baseline and group
Time frame: 10 to 21 days (assessment is conducted once before the intervention and repeated three times afterwards, i.e. 3, 7 and 14 days after the completion of the intervention)
Endurance performance VI
Change of running economy (in ml/min/kg) compared to baseline and group
Time frame: 10 to 21 days (assessment is conducted once before the intervention and repeated three times afterwards, i.e. 3, 7 and 14 days after the completion of the intervention)
Change of questionnaire scores - well-being
Change of questionnaire scores compared to baseline and group as determined by a Visual-Analogue-Scale (from 0-100 millimeters). Higher scores indicate poorer well-being.
Time frame: 30 days (questionnaires will be given to participants several times before, during, and after the intervention.)
Change of questionnaire scores - muscular fatigue
Change of questionnaire scores compared to baseline and group as determined by a Visual-Analogue-Scale (from 0-100 millimeters). Higher scores indicate higher degree of fatigue.
Time frame: 30 days (questionnaires will be given to participants several times before, during, and after the intervention.)
Change of questionnaire scores - vitality
Change of questionnaire scores compared to baseline and group as determined by a Likert-Scale (from 0-10). Higher scores indicate higher vitality.
Time frame: 30 days (questionnaires will be given to participants several times before, during, and after the intervention.)
Change of questionnaire scores - rate of fatigue
Change of questionnaire scores compared to baseline and group as determined by a Likert-Scale (from 0-10). Higher scores indicate higher degree of fatigue.
Time frame: 30 days (questionnaires will be given to participants several times before, during, and after the intervention.)
Change of questionnaire scores - sleep quality
Change of questionnaire scores compared to baseline and group as determined by a Likert-Scale (from 1-7). Higher scores indicate poorer sleep.
Time frame: 30 days (questionnaires will be given to participants several times before, during, and after the intervention.)
Change of blood count
Change of blood count concentrations compared to baseline and group
Time frame: 30 days (blood is drawn from participants several times before, during, and after the intervention.)
Change of cell-free DNA
Change of cell-free DNA concentrations compared to baseline and group
Time frame: 30 days (blood is drawn from participants several times before, during, and after the intervention.)
Change of creatine kinase
Change of creatine kinase concentrations compared to baseline and group
Time frame: 30 days (blood is drawn from participants several times before, during, and after the intervention.)
Change of urea
Change of urea concentrations compared to baseline and group
Time frame: 30 days (blood is drawn from participants several times before, during, and after the intervention.)
Change of blood lactate
Change of blood lactate concentrations compared to baseline and group
Time frame: 30 days (blood is drawn from participants several times before, during, and after the intervention.)
Change of cytokines
Change of cytokine concentrations compared to baseline and group
Time frame: 30 days (blood is drawn from participants several times before, during, and after the intervention.)
Change of miRNA
Change of miRNA compared to baseline and group
Time frame: 30 days (blood is drawn from participants several times before, during, and after the intervention.)
Change of neuromuscular performance
Change of neuromuscular performance (counter movement jump height in cm) measured on a contact plate (AMTI, Watertown, USA) compared to baseline and group
Time frame: 30 days (neuromuscular performance is assessed several times before, during, and after the intervention)
Change of body weight
Change of body weight in kg compared to baseline and group
Time frame: 10 to 21 days (assessment is conducted once before the intervention and repeated three times afterwards, i.e. 3, 7 and 14 days after the completion of the intervention)
Change of fat free mass
Change of fat free mass in kg compared to baseline and group
Time frame: 10 to 21 days (assessment is conducted once before the intervention and repeated three times afterwards, i.e. 3, 7 and 14 days after the completion of the intervention)
Change of fat mass
Change of fat mass in kg compared to baseline and group
Time frame: 10 to 21 days (assessment is conducted once before the intervention and repeated three times afterwards, i.e. 3, 7 and 14 days after the completion of the intervention)
Change of forced expiratory volume
Change of forced expiratory volume in liters compared to baseline and group
Time frame: 10 to 21 days (assessment is conducted once before the intervention and repeated three times afterwards, i.e. 3, 7 and 14 days after the completion of the intervention)
Change of power output during exercise
Change of power output in Watt (as determined via Stryd, Boulder, USA) during the intervention compared to baseline and group
Time frame: 7 days
Change of sleep quality I - GPS watch
Change of sleep quality compared to baseline and group as determined by a GPS (Global Positioning System) watch
Time frame: 30 days (sleep is assessed several times before, during, and after the intervention)
Change of sleep quality II - ABIOS App
Change of sleep quality compared to baseline and group as determined by the ABIOS (Algorithmik Biodata System) application
Time frame: 30 days (sleep is assessed several times before, during, and after the intervention)
Correlations between sleep quality devices
To determine the correlations between different sleep monitoring devices, i.e. the GPS watch (see outcome 27), the ABIOS system (see outcome 28) and the sleep quality questionnaire (see outcome 11)
Time frame: 30 days
Change of parameters recorded by an electrocardiogram - mean heart rate
Change of mean heart rate compared to baseline and group
Time frame: 30 days (an electrocardiogram is written several times before, during, and after the intervention)
Change of parameters recorded by an electrocardiogram - heart rate variability
Change of heart rate variability (root mean sum of squared distance in ms) compared to baseline and group
Time frame: 30 days (an electrocardiogram is written several times before, during, and after the intervention)
Change of executive functions - Eriksen flanker task
Change of executive functions compared to baseline and group. This is recorded through a modified Eriksen flanker task consisting of 108 images showing five white arrows on a black screen.
Time frame: 30 days (executive functions are tested several times before, during, and after the intervention)
Change of executive functions - 2 back task
Change of executive functions compared to baseline and group. This is assessed through a 2-back task showing dots on a dice, numbers and geometrical figures.
Time frame: 30 days (executive functions are tested several times before, during, and after the intervention)
Cardiac ultrasound
Description of an athlete cohort regarding cardiac chamber volume (in ml, determined via EPIQ CVX, X5-1, Philips Healthcare, Andover, MA, USA)
Time frame: 1 day (this outcome will be determined once before study start)
Adherence to training program
Adherence to the HIIT training programs (determined as the ratio of training sessions performed to prescribed training sessions). This is determined by the researchers by checking the training data of the athletes. For example, if 9 out of 10 sessions were performed, this means 90% adherence.
Time frame: 7 days
Plan to share: No
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University of Salzburg