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Active, not recruitingNCT05045157SECOIAUpdated Jun 2, 2026

Effectiveness of Percutaneous Pulley Release With Infiltration, Versus Infiltration Alone in Trigger Finders

An interventional study of Percutaneous A1 Pulley Release Under Ultrasound Guidance and Corticosteroid injection in Trigger Finger, sponsored by Centre Hospitalier Departemental Vendee. Active, not recruiting at 4 sites in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-06-02.

Sponsored by Centre Hospitalier Departemental Vendee · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
50
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

Trigger finger is a mechanical problem characterized by pain and catching of digit in flexion.

Histological changes of A1 pulley and synovial proliferation have been identified as factors that prompt trigger finger The first-line treatment of trigger finger is conservative with splinting and corticosteroid injection.

If the first infiltration fails, either a second infiltration or surgical sectioning of the pulley is proposed.

Surgery can be performed by several techniques (open section, percutaneous section with palpatory guidance, or under ultrasound guidance).

Percutaneous A1 pulley release under ultrasound guidance consists of cutting the A1 pulley by a percutaneous insertion with small needle under local anaesthesia.

The hypothesis of the study is that percutaneous A1 pulley release under ultrasound guidance followed by a corticosteroid injection would be more effective than a second corticosteroid injection alone on complete resolution of the trigger finger symptoms

02

Conditions studied

  • Trigger Finger
03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Patient ≥ 18 years old,
  • Presence of a trigger finger (thumb or long fingers) to be treated
  • Quinnell score >1
  • Episode of trigger characterized on questioning or clinical examination
  • Failure of a first corticosteroid infiltration > 3 months before inclusion
  • First infiltration within 15 months of inclusion
  • Thickening A1 pulley on ultrasound ≥ 0.5 mm
  • Patient who has the capacity to understand the protocol and has given consent to participate in the research,
  • Patient with social security coverage

Exclusion criteria

Exclusion Criteria:

  • Presence of several symptomatic fingers requiring treatment by ultrasound-guided section of the pulley
  • Patient who are pregnant, breastfeeding, or who have the potential to become pregnant without effective contraception at the time of inclusion
  • Known allergy to corticoid (Hydrocortancyl®) including its excipients ((benzyl alcohol, sodium carmellose, sodium chloride, polysorbate 80)
  • Known allergies to lidocaine
  • Ongoing anticoagulant treatments (AVK, New Oral Anti-Coagulants)
  • Local or general infection, or suspicion of infection
  • Live vaccines
  • Evolving viruses (hepatitis, herpes, varicella, shingles)
  • Severe or uncontrolled hypertension
  • Unbalanced diabetes
  • Underlying progressive cardiovascular disease
  • Hemodialysis patients
  • Prosthesis on the finger to be treated
  • Echographic tendon fissure
  • Inflammatory disease (rheumatoid arthritis, spondyloarthritis, connective tissue diseases, etc.) with tenosynovitis.
  • History of surgery on the fingers
  • Dupuytren's disease
  • Patient participating in another interventional clinical research protocol involving a drug or medical device
  • Patient under guardianship, curators or legal protection
04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
50 participants (actual)

Study arms

  • Experimental
    percutaneous A1 pulley release with corticosteroid injection

    Procedure: Percutaneous A1 Pulley Release Under Ultrasound Guidance · Drug: Corticosteroid injection

  • Active comparator
    corticosteroid injection alone

    Drug: Corticosteroid injection

Interventions

  • ProcedurePercutaneous A1 Pulley Release Under Ultrasound Guidance

    the A1 pulley is cut off with Ultrasound guidance by a percutaneous insertion of the small needle under local anaesthesia.

  • DrugCorticosteroid injection

    corticosteroid injection is performed

05

What researchers measure

Primary outcomes

  1. Effectiveness of pulley section with ultrasound guidance combined with corticosteroid infiltration versus corticosteroid alone on complete resolution of trigger finger's symptoms

    Trigger finger's symptoms defined by a clinical Quinnell score ≤1 without the use of an alternative therapy

    Time frame: 1 year postoperatively

06

Study locations

4 sites
  • Hopital Henri Mondor
    Créteil, 94000, France
  • CHD Vendée
    La Roche-sur-Yon, 85925, France
  • CHU Nantes
    Nantes, 44000, France
  • Hopital Lariboisière
    Paris, 75010, France
07

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT05045157
Lead sponsor
Centre Hospitalier Departemental Vendee
Responsible party
Sponsor
First posted
Sep 16, 2021
Start date
May 31, 2022
Primary completion
May 31, 2026
Completion
May 31, 2027 (estimated)
Last update
Jun 2, 2026

Study contacts

Grégoire Cormier, Dr
principal investigator · CHD Vendée

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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