An observational study in Coronary Artery Bypass, sponsored by Ruijin Hospital. Completed at 1 site in China. Per ClinicalTrials.gov, last updated 2024-12-12.
Sponsored by Ruijin Hospital · Observational
Review the data of patients who underwent coronary artery bypass grafting (CABG) at the Department of Cardiovascular Surgery in Ruijin hospital from March 2020 to May 2022, including medical history, head and neck CTA, head CT scan, and early postoperative (within 7 days after surgery) neurological complications (defined as a composite of stroke, delayed awakening and severe delirium) . Case-control and retrospective cohorts were built to explore risk factors of early postoperative neurological complications, And its association with baseline carotid-cerebral vascular disease.
Describe the epidemiological data of early postoperative neurological complications (stroke, delayed awakening, and severe delirium) after CABG surgery (within 7 days after surgery); explore independent risk factors of compound neurological complications, build predictive models; compare the effects of carotid-cerebral artery disease on early postoperative compound neurological complications.
1,027 studies on the registry are indexed under Vascular Diseases; 167 are open to participants now.
This study's enrollment of 1,002 is above the median of 200 across 301 observational studies indexed under Vascular Diseases.
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Patients received CABG at the department of cardiac surgery in Ruijin hospital.
Exclusion Criteria:
moderate (stenosis 50-69%) or severe (stenosis 70-100%) carotid-cerebral artery disease
mild (stenosis 30-49%) or no (stenosis 0-29%) carotid-cerebral artery disease
the incidence of 7-day neurological complications
a composite of stroke, delayed awakening, severe delirium
Time frame: within 7 days post-CABG
the incidence of 7-day stroke
including cerebral infarction, cerebral hemorrhage, and hypoxic-ischemic encephalopathy
Time frame: within 7 days post-CABG
the incidence of delayed awakening
post-surgery patient does not wake up at 48 hours after withdrawing sedative
Time frame: within 48 hours post-CABG
the incidence of severe delirium
ICU CAM-II score≥2 points
Time frame: within 7 days post-CABG
the incidence of All-cause death
Death from any cause
Time frame: 7 days, 30 days and 1 year post-CABG
the incidence of CV-death
Including death resulting from an acute myocardial infarction , sudden cardiac death, death due to heart failure, death due to stroke, death due to cardiovascular procedures, death due to cardiovascular hemorrhage, and death due to other cardiovascular causes
Time frame: 7 days, 30 days and 1 year post-CABG
the incidence of myocardial infraction
According to the 2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials, including CABG-related MI, non CABG-related MI, silent MI and unknown type.
Time frame: 7 days, 30 days and 1 year post-CABG
the incidence of repeat revascularization
any PCI and CABG.
Time frame: 7 days, 30 days and 1 year post-CABG
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Dec 2024. You cannot join it, but the record below documents what was studied.
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Ruijin Hospital