ClinicalTrials.gg
Status unknownNCT04988113Updated Aug 3, 2021

Presentation And Management Of Neglected Inhaled Foreign Body At Sohag University Hospital

An observational study in Foreign Body; Inhalation, sponsored by Sohag University. Status unknown at 1 site in Egypt. Per ClinicalTrials.gov, last updated 2021-08-03.

Sponsored by Sohag University · Observational

The sponsor has not verified this record recently (last verified Jul 2021), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Other
Time perspective
Retrospective
Enrollment
60
Sex
All
01

Study summary

Delayed presentation is not uncommon in children and may have been treated as asthma due to associated with low-grade cough and noisy breathing.

Late diagnoses of foreign body aspiration were defined as occurring beyond 3 days after the aspiration of the foreign body, or onset of symptoms.

Undiagnosed foreign body aspiration can cause mechanical effects, chemical reactions, and the most common complications were pneumonia, asthma, lung collapse, bronchiectasis, emphysema, mediastinal shift, atelectasis and lung abscess. Long-term presence of FBs in the bronchus may lead to bronchial stenosis

Read the detailed description

A foreign body is an endogenous or exogenous substance, different from the anatomy of the site where it is found. Chevalier Jackson defined a foreign body as "an object or a substance that is foreign to its location".

Aspiration of a foreign body (FB) is a potentially life-threatening emergency and 75% of cases occur in children younger than 3 years of age, due to the absence of molar teeth, underdeveloped swallowing coordination and the tendency to talk and play while eating .

However, foreign body aspiration does happen in adults and elderly people as well.

Obtaining a good history plays a vital role in effectively diagnosing a foreign body aspiration. Three clinical phases of aspiration of foreign bodies are recognized: The first stage is the impaction of the foreign body and entitled "penetration syndrome," defined as a sudden onset of choking and intractable cough with or without vomiting.

In the second stage, these symptoms diminish as the foreign body settles into a stationary location and the tracheoesophageal reflexes tire out; this asymptomatic stage can last hours to weeks, which may delay diagnosis. In the third phase, Complications occur (also defined as Complications phase), when obstruction, erosion or infection cause pneumonia, atelectasis, abscess or fever. The first presentation of the condition may actually represent a complication of inhaled foreign body.

Delayed presentation is not uncommon in children and may have been treated as asthma due to associated with low-grade cough and noisy breathing.

Late diagnoses of foreign body aspiration were defined as occurring beyond 3 days after the aspiration of the foreign body, or onset of symptoms.

Undiagnosed foreign body aspiration can cause mechanical effects, chemical reactions, and the most common complications were pneumonia, asthma, lung collapse, bronchiectasis, emphysema, mediastinal shift, atelectasis and lung abscess. Long-term presence of FBs in the bronchus may lead to bronchial stenosis.

Neglected foreign bodies in the respiratory tract may occur due to misdiagnosis by the fellow professionals and pediatricians when FBs in the upper tracheal airway produce symptoms similar to those of viral subglottic croup or due to lack of typical symptoms and signs. The most common symptoms and signs of FBA, namely coughing, wheezing, and decreased air entry, can easily be overlooked by bronchial asthma or pneumonia. Parental negligence, not conclusive chest radiographs, and false negative bronchoscopic findings are other blamed factors

02

Conditions studied

  • Foreign Body; Inhalation

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03

In context

Respiratory Aspiration

25 studies on the registry are indexed under Respiratory Aspiration; 6 are open to participants now.

Browse Respiratory Aspiration studies →

Lead sponsor

Sohag University is the lead sponsor of 1,232 studies on the registry; 638 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients who were diagnosed with neglected inhaled foreign body who underwent bronchoscopy in sohag university hospital

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

Patients who were diagnosed with neglected inhaled foreign body who underwent bronchoscopy in sohag university hospital, all ages, both Gender.

Exclusion criteria

Exclusion Criteria:

Patients who were diagnosed with recent inhaled foreign body.

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Study design

Observational model
Other
Time perspective
Retrospective
Enrollment
60 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Assessment of different pictures of clinical presentations in neglected inhaled foreign body.

    This is a retrospective study that will be conducted in our tertiary center "Sohag University Hospital", will include cases of neglected inhaled foreign bodies in the period from June 2016 to June 2021, the medical records of patients who underwent bronchoscopy for suspected neglected foreign body aspiration will be reviewed. Assessment of different pictures of clinical presentations by reviewed symptoms and signs for the cases.

    Time frame: 3 months from August to December 2021

  2. Determination of types of complications in neglected inhaled foreign body.

    This is a retrospective study that will be conducted in our tertiary center "Sohag University Hospital", will include cases of neglected inhaled foreign bodies in the period from June 2016 to June 2021, the medical records of patients who underwent bronchoscopy for suspected neglected foreign body aspiration will be reviewed. Determination of types of complications in neglected inhaled foreign body.

    Time frame: 3 months from August to December 2021

  3. Determination of different types of management plans in neglected inhaled foreign body.

    This is a retrospective study that will be conducted in our tertiary center "Sohag University Hospital", will include cases of neglected inhaled foreign bodies in the period from June 2016 to June 2021, the medical records of patients who underwent bronchoscopy for suspected neglected foreign body aspiration will be reviewed. Determination of different types of management plans by rigid or flexible bronchoscopic findings, including the type and the location of the foreign body

    Time frame: 3 months from August to December 2021

07

Study locations

1 of 1 sites recruiting
  • Sohag University
    Sohag, Egypt
    Recruiting
    • usama R El-Sherif, professor · Contact
08

References and documents

Publications

  • Adjeso T, Damah MC, Murphy JP, Anyomih TTK. Foreign Body Aspiration in Northern Ghana: A Review of Pediatric Patients. Int J Otolaryngol. 2017;2017:1478795. doi: 10.1155/2017/1478795. Epub 2017 Oct 1. PubMed 29098005 ↗
  • Lin L, Lv L, Wang Y, Zha X, Tang F, Liu X. The clinical features of foreign body aspiration into the lower airway in geriatric patients. Clin Interv Aging. 2014 Sep 24;9:1613-8. doi: 10.2147/CIA.S70924. eCollection 2014. PubMed 25284994 ↗
  • Salih AM, Alfaki M, Alam-Elhuda DM. Airway foreign bodies: A critical review for a common pediatric emergency. World J Emerg Med. 2016;7(1):5-12. doi: 10.5847/wjem.j.1920-8642.2016.01.001. PubMed 27006731 ↗

Individual participant data

Plan to share: No

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Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Start is estimated for Aug 2021; primary completion for Dec 2021, 4 months later.

How these figures are worked out, and which studies are left out of them.

Registered
Jul 13, 2021
First posted
Aug 3, 2021
StartEst.
Aug 1, 2021
Primary completionEst.
Dec 1, 2021
CompletionEst.
Dec 1, 2021
Last update
Aug 3, 2021
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Aug 3, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04988113
Lead sponsor
Sohag University
Responsible party
Abdallah Mohamed Ahmed (resident, Sohag University) — Principal investigator
First posted
Aug 3, 2021
Start date
Aug 1, 2021 (estimated)
Primary completion
Dec 1, 2021 (estimated)
Completion
Dec 1, 2021 (estimated)
Last update
Aug 3, 2021

Study contacts

Abdallah M Ahmed, resident
Contact
abdallah.ahmed@med.sohag.edu.eg
01098720110
Mostafa A Mohamed, professor
Contact
01032713236
Abdel-Mateen M Abd ElLateef, professor
study chair · Sohag University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is status unknown, as verified in Jul 2021. You cannot join it, but the record below documents what was studied.

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