An observational study in Adult Hospital Patients at Risk of Adverse Outcomes, sponsored by Portsmouth Hospitals NHS Trust. Recruiting at 1 site in United Kingdom. Open to participants aged 16 Years and older. Per ClinicalTrials.gov, last updated 2026-06-29.
Sponsored by Portsmouth Hospitals NHS Trust · Observational
An integrated database of depersonalised routine hospital patient data consisting of demographic and disease attributes, physiological or laboratory measurements, care contacts and interventions along with associated clinical outcomes. The database is an essential resource for the development and testing of risk models and classification systems, modified as necessary for patient subgroups, which can then be introduced into clinical care to improve patient outcomes. It can also be used for large scale simulations to evaluate interventions.
The aims and objectives of this database of depersonalised routinely collected hospital patient data are to:
Portsmouth Hospitals NHS Trust is the lead sponsor of 74 studies on the registry; 15 are open to participants now.
Counted across the registry records on this site, refreshed daily.
The research database will hold data on adults who are treated by Portsmouth Hospitals University National Health Service Trust (PHU), either as an outpatient, Accident and Emergency (A\&E) attender, day case or inpatient or have investigations carried out by PHU services Adult patients are defined by the National Health Service (NHS) as individuals over 16 years old. Data on service contacts and use will only be included where the patient was more than 16 years old at that time. None of the data included in the Clinical Outcomes analyses are collected specifically for the purposes of research. All datasets are routinely collected clinical datasets, collected for clinical use and clinical audit.
Exclusion Criteria:
In-hospital death
Death during hospital admission
Time frame: At 24 hours after an observation assessment or physiological measurement
In-hospital death
Death during hospital admission
Time frame: 30 days after admission
Unanticipated ICU admission
Unanticipated ICU admission during hospital stay
Time frame: At 24 hours after an observation assessment or physiological measurement
Unanticipated ICU admission
Unanticipated ICU admission during hospital stay
Time frame: 30 days after admission
Cardiac arrest
Cardiac arrest during hospital stay
Time frame: At 24 hours after an observation assessment or physiological measurement
Cardiac arrest
Cardiac arrest during hospital stay
Time frame: 30 days after admission
Diagnosis of Corona Virus Disease (COVID) infection
Diagnosis of COVID-19
Time frame: 48 hours after presentation
Diagnosis of Corona Virus Disease (COVID) infection
Diagnosis of COVID-19
Time frame: At 48 hours after an observation assessment or physiological measurement
Detection of Acute Organ Dysfunction
Detection of acute organ dysfunction as measured by components of the Sequential Organ Failure Assessment (SOFA) Score
Time frame: 24 hours after presentation
Detection of Acute Organ Dysfunction
Detection of acute organ dysfunction as measured by components of the Sequential Organ Failure Assessment (SOFA) Score
Time frame: 48 hours after presentation
Detection of Acute Organ Dysfunction
Detection of acute organ dysfunction as measured by components of the Sequential Organ Failure Assessment (SOFA) Score
Time frame: 72 hours after presentation
Detection of Acute Organ Dysfunction
Detection of acute organ dysfunction as measured by components of the Sequential Organ Failure Assessment (SOFA) Score
Time frame: 1 week after presentation
Detection of Acute Organ Dysfunction
Detection of acute organ dysfunction as measured by components of the Sequential Organ Failure Assessment (SOFA) Score
Time frame: 30 days after presentation
Plan to share: Undecided — Bona fides United Kingdom (UK) researchers can make requests for access. They will be asked to detail their proposal in standard form which will be assessed by a Data Access Committee. Data will only be made available in a fully anonymous form and will be subject to a data sharing agreement.
No publications or documents are linked to this record.
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Portsmouth Hospitals NHS Trust