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Status unknownNCT04976517Updated Jul 26, 2021

Echocardiographic Assessment of the Impact of Diabetes and Prognostic Analysis of Heart Transplantation

An observational study in Heart Transplant, sponsored by Xie Mingxing. Status unknown. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2021-07-26.

Sponsored by Xie Mingxing · Observational

The sponsor has not verified this record recently (last verified Jul 2021), so the status shown — last known as Not yet recruiting — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
1,500
Ages
18 Years and older
Sex
All
01

Study summary

The aim of this study is to evaluat the impact of diabetes on cardiac function in patients with heart transplantation by multimodal imaging and analyse their prognosis.

Read the detailed description

This study is planed to enroll 300000 patients after heart transplantation, all the patients will be divided into 3 groups according to whether or not they have diabetes and when did they develop diabete. Echocardiography will be used to evaluat their cardiac function. Comparing their cardiac function and clinical information and analysing their prognosis to evaluat the impact of diabetes.

02

Conditions studied

  • Heart Transplant
03

In context

Lead sponsor

Xie Mingxing is the lead sponsor of 5 studies on the registry; 4 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Adult patients who received a heart transplant after 2015

Inclusion criteria

  • Adult patients who received a heart transplant after 2015

Exclusion criteria

Exclusion Criteria:

  • The image quality is poor
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
1,500 participants (estimated)
Patient registry
No

Groups and cohorts

  • non-diabetes group

    patients who underwent heart tranplantation without diabetes

  • pre-transplant diabetes group

    patients who underwent heart tranplantation with diabetes before the transplantation

  • post transplant daibetes group

    patients who underwent heart tranplantation without diabetes until after the transplantation

06

What researchers measure

Primary outcomes

  1. all-cause mortality

    death from all causes

    Time frame: up to 2023.12

  2. acute rejection

    acute rejection required treatment

    Time frame: up to 2023.12

  3. readmission

    readmission from all causes

    Time frame: up to 2023.12

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 26, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT04976517
Lead sponsor
Xie Mingxing
Collaborators
Second Affiliated Hospital, School of Medicine, Zhejiang University, Shanghai Zhongshan Hospital, Wuhan Asia Heart Hospital, Guangdong Provincial People's Hospital, Henan Provincial People's Hospital
Responsible party
Xie Mingxing (MD, PhD,FACC, FAHA, FASE, Wuhan Union Hospital, China) — Sponsor-investigator
First posted
Jul 26, 2021
Start date
Aug 1, 2021 (estimated)
Primary completion
Dec 31, 2023 (estimated)
Completion
Mar 31, 2024 (estimated)
Last update
Jul 26, 2021

Study contacts

Li Zhang, PhD
Contact
zli429@hust.edu.cn
18907131488
Li Zhang, PhD
principal investigator · Department of Ultrasound, Union Hospital, Wuhan, China

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Jul 2021. You cannot join it, but the record below documents what was studied.

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