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CompletedNCT04961489Updated Jul 14, 2021

Impact of Measures Taken to Contain COVID-19 on Hospital Surgical Care Services and Clinical Outcomes

An observational study in Surgery, sponsored by National Cancer Centre, Singapore. Completed at 2 sites in Singapore. Open to participants aged 21 Years to 100 Years. Per ClinicalTrials.gov, last updated 2021-07-14.

Sponsored by National Cancer Centre, Singapore · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
11,000
Ages
21 Years to 100 Years
Sex
All
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Study summary

This study aims to look at the impact on patient outcomes arising from measures implemented during the COVID-19 pandemic. The information and knowledge from this study will be useful for the management and allocation of hospital resources and patients in tne event of a disease outbreak.

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Conditions studied

  • Surgery

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Keywords

  • Covid-19 pandemic
  • emergency
  • cancer
  • elective surgery
  • postponement
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In context

COVID-19

7,640 studies on the registry are indexed under COVID-19; 488 are open to participants now.

This study's enrollment of 11,000 is above the median of 261 across 3,136 observational studies indexed under COVID-19.

Browse COVID-19 studies →

Lead sponsor

National Cancer Centre, Singapore is the lead sponsor of 116 studies on the registry; 30 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
21 Years to 100 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

This study seeks to assess the effect of the measures taken to contain COVID 19 on patients who need surgical services measured by patient outcomes, such as, length of hospital stay (LOS), ICU stay, APACHE score, and stage of cancer at surgery.

Inclusion criteria

  • This study involves the extraction of patient records from the enterprise dataware house. As such, we do not stipulate the age limits.
  • Patients who had the following surgeries during over the period of 1 Jan 2017 to 31 December 2020
  • From the identified surgical procedure type or the following cancer-related procedures:

    1. Breast
    2. Colon
    3. Liver
    4. Rectum
  • Selected non-cancer surgeries:

    1. Abdominal Wall
    2. Gallbladder
  • Patients from SGH and its related institute NCC
  • Only local Singapore Citizens

Exclusion criteria

Exclusion Criteria:

  • No exclusion criteria
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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
11,000 participants (actual)
Patient registry
No
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What researchers measure

Primary outcomes

  1. Analysis of patients according to type of surgical procedures, medical condition and dates of surgical treatment retrospectively.

    These patients are classified according to the institution, type of surgical procedures, the medical condition and the dates of surgical treatment. The study will be compared across four time periods.

    Time frame: 1 Jan - 31 Dec 2017, 1 Jan - 31 Dec 2018, 1 Jan - 31 Dec 2019, 1 Jan - 31 Dec 2020

  2. Comparing surgical indices for high volume cancer and non-cancer diagnoses

    The study focus on surgical indices for selected high-volume cancer and non-cancer diagnoses over the period 1st January2020 to 31 December 2020 and compare them with similar indices across the same period of time in the preceding 3 years in particular, for the following surgical procedures: 1. Surgeries for the following cancer diagnoses: 1. breast cancer, \[XIV- N60, no malignancy\], \[Malignant, IINeoplasms- C50\], colorectal cancer, \[C18, 19, 20\], 2. hepatocellular carcinoma, \[C22\] 2. Selected non-cancer surgeries: 1. Cholecystectomy 2. Abdominal hernia repair

    Time frame: 1 Jan 2020 - 31 Dec 2020

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Study locations

2 sites
  • Singapore General Hospital
    Singapore, 169608, Singapore
  • National Cancer Center Singapore
    Singapore, 169690, Singapore
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References and documents

Publications

  • Mazingi D, Navarro S, Bobel MC, Dube A, Mbanje C, Lavy C. Exploring the Impact of COVID-19 on Progress Towards Achieving Global Surgery Goals. World J Surg. 2020 Aug;44(8):2451-2457. doi: 10.1007/s00268-020-05627-7. PubMed 32488665 ↗
  • Al-Jabir A, Kerwan A, Nicola M, Alsafi Z, Khan M, Sohrabi C, O'Neill N, Iosifidis C, Griffin M, Mathew G, Agha R. Impact of the Coronavirus (COVID-19) pandemic on surgical practice - Part 2 (surgical prioritisation). Int J Surg. 2020 Jul;79:233-248. doi: 10.1016/j.ijsu.2020.05.002. Epub 2020 May 12. PubMed 32413502 ↗

Individual participant data

Plan to share: No

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 14, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04961489
Lead sponsor
National Cancer Centre, Singapore
Collaborators
National Medical Research Council (NMRC), Singapore
Responsible party
Sponsor
First posted
Jul 14, 2021
Start date
Aug 1, 2020
Primary completion
Mar 31, 2021
Completion
Mar 31, 2021
Last update
Jul 14, 2021

Study contacts

Pierce Chow, MD, PhD
principal investigator · National Cancer Centre, Singapore

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2021. You cannot join it, but the record below documents what was studied.

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