An interventional study of Cognitive Training in Anxiety Disorders, sponsored by University of California, San Diego. Completed at 1 site in United States. Open to participants aged 18 Years to 55 Years. Per ClinicalTrials.gov, last updated 2021-10-01.
Sponsored by University of California, San Diego · Not applicable, Interventional, and Basic science
Anxiety disorders are highly prevalent and costly to the individual and society. Exposure-based cognitive behavioral therapy (CBT) is the gold-standard intervention for anxiety disorders, although this approach does not fully reduce symptoms for all individuals. Therefore there is a need for innovative intervention approaches. One approach to augment and improve existing therapies would be to enhance the neurocognitive basis of fear extinction processes, which are the model on which treatments are based. Enhancing these processes may be possible through computerized cognitive training techniques which target executive functioning, the cognitive processes that help people manage complex cognitive activities. The proposed project is a proof-of-concept pilot study investigating the potential for training of executive functioning to improve anxiety-related outcomes. Individuals with elevated levels of social anxiety will be randomized to single-session COGnitive Enhancement Training (COGENT) or sham training program (ST). All participants will complete a single speech session where they present three 7-minute impromptu speeches and rate their anxiety at specific intervals. Participants will then complete the COGENT paradigm and affective processing task while undergoing fMRI.
4,868 studies on the registry are indexed under Anxiety Disorders; 1,390 are open to participants now.
This study's enrollment of 30 is below the median of 80 across 4,174 interventional studies indexed under Anxiety Disorders.
Browse Anxiety Disorders studies →University of California, San Diego is the lead sponsor of 958 studies on the registry; 191 are open to participants now.
Of its 110 completed or terminated interventional studies of FDA-regulated products, 70 (64%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Participants will complete adaptive computerized cognitive training plus a series of speech tasks
Behavioral: Cognitive Training
Participants will complete a low-dose computerized cognitive program plus a series of speech tasks
Behavioral: Cognitive Training
Participants are asked to remember a series of items while solving puzzles.
BOLD activation during cognitive task
Working Memory Span task during fMRI
Time frame: immediately after the intervention
BOLD activation during emotional task
Face processing task during fMRI
Time frame: immediately after the intervention
Speech anxiety ratings
Subjective units of distress, scaled from 0 to 100, during each of 3, 7-minute speech activities
Time frame: baseline, ratings during 3 speeches
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Sep 2021. You cannot join it, but the record below documents what was studied.
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University of California, San Diego