ClinicalTrials.gg
Status unknownNCT04951011Updated Jul 6, 2021

Different Treatment Options for Tubal Ectopic Pregnancy:- A Systmatic Review

An observational study in Woman With Tubal Ectopic Pregnancy, sponsored by Sohag University. Status unknown at 1 site in Egypt. Open to female participants aged 15 Years to 40 Years. Per ClinicalTrials.gov, last updated 2021-07-06.

Sponsored by Sohag University · Observational

The sponsor has not verified this record recently (last verified Jul 2021), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Case-control
Time perspective
Cross-sectional
Enrollment
50
Ages
15 Years to 40 Years
Sex
Female
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Study summary

Ectopic pregnancy is an early pregnancy complication in which a fertilized ovum implant outside the uterine cavity. Implantation may occur anywhere along the reproductive tract with the most common implantation site being the fallopian tube. The incidence of ectopic pregnancy is 1% of pregnant women, and may seriously compromise women's health and future fertility.

Currently, ectopic pregnancy can be often diagnosed before the woman's condition has deteriorated, which has altered the former clinical picture of a lifethreatening disease into a more benign condition in frequently asymptomatic women.

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Conditions studied

  • Woman With Tubal Ectopic Pregnancy

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In context

Pregnancy, Ectopic

83 studies on the registry are indexed under Pregnancy, Ectopic; 21 are open to participants now.

This study's planned enrollment of 50 is below the median of 150 across 39 observational studies indexed under Pregnancy, Ectopic.

Browse Pregnancy, Ectopic studies →

Lead sponsor

Sohag University is the lead sponsor of 1,230 studies on the registry; 636 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
15 Years to 40 Years
Sexes eligible
Female
Sampling method
Probability sample

Study population

Sample size: All articles fulfilling the inclusion criteria within the last five years.

Study tools: Primary data will be re-analyzed statistically and processed data to be compared. Secondary data will be analyzed for correlation between the type of anastomosis (hand sewing vs. staplers) and between measurements outcome (leakage and, stricture and fistula formation).

  • Study procedure: The study will start by searching articles using the key words and then downloading papers that fulfill the inclusion criteria and excluding papers with exclusion criteria. These papers will be examined by the supervisors to make sure of finding the appropriate source of data and then I will start working with the statistical supervisor and put data on R-based software for meta-analysis and start conducting the study.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • RCTs and observational studies
  • All types of ectopic pregnancies.
  • All types of treatments and medications for ectopic pregnancies.
  • The long-term survival of patients with or without complications.
  • Successful pregnancy and birth.

Exclusion criteria

Exclusion criteria:

  • Articles of failed treatments of ectopic pregnancies.
  • Articles with over all P value > 0.05.
  • Articles for which the full text is not available in English.
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Study design

Observational model
Case-control
Time perspective
Cross-sectional
Enrollment
50 participants (estimated)
Patient registry
No

Interventions

  • Diagnostic testSerum beta HCG

    Raising numbers of S BHCG or decreasing with different management of tubal Ectopic Pregnancy

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What researchers measure

Primary outcomes

  1. Abdominal and Transvaginal Ultrasound:

    To detect the appearance of any mass at the adenexa,or intrauterine gestational sac in case of heterotopic pregnancy or misdiagnosis of ectopic pregnancy. To detect, if there's collection at the pelvis or freely at the abdomen in the case of disturbed ectopic pregnancy.

    Time frame: 6 Monthes

  2. S.bHCG:

    in cases of expectant management,and medical treatment to detect level of S.bHCG after administration of methotrexate to decide to continue with medical treatment and give another doses or failure of this line and decide another line of management. Also,at the expectant management to close follow up the patient.

    Time frame: 6 Monthes

  3. Diagnostic laparoscopy

    In cases of early,undisturbed ectopic pregnancy and may use also,for therapy Laparoscopic salpingostomy and/or salpingectomy

    Time frame: 6 Monthes

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Study locations

1 of 1 sites recruiting
  • Sohag
    Akhmim, Egypt
    Recruiting
    • Hassan Noman, professor · Contact
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References and documents

Publications

  • Barnhart KT. Clinical practice. Ectopic pregnancy. N Engl J Med. 2009 Jul 23;361(4):379-87. doi: 10.1056/NEJMcp0810384. No abstract available. PubMed 19625718 ↗
  • Bagshawe KD, Dent J, Newlands ES, Begent RH, Rustin GJ. The role of low-dose methotrexate and folinic acid in gestational trophoblastic tumours (GTT). Br J Obstet Gynaecol. 1989 Jul;96(7):795-802. doi: 10.1111/j.1471-0528.1989.tb03318.x. PubMed 2548568 ↗
  • Elson J, Tailor A, Banerjee S, Salim R, Hillaby K, Jurkovic D. Expectant management of tubal ectopic pregnancy: prediction of successful outcome using decision tree analysis. Ultrasound Obstet Gynecol. 2004 Jun;23(6):552-6. doi: 10.1002/uog.1061. PubMed 15170794 ↗

Individual participant data

Plan to share: Yes

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 6, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04951011
Lead sponsor
Sohag University
Responsible party
Mohamed Abdelhameed Mohamed (resident doctor at obstitrics and gyncology department sohag university hospital, Sohag University) — Principal investigator
First posted
Jul 6, 2021
Start date
Jul 1, 2021 (estimated)
Primary completion
Jan 1, 2022 (estimated)
Completion
Jan 1, 2022 (estimated)
Last update
Jul 6, 2021

Study contacts

Mohamed A Mohamed, Master
Contact
mohamed011161@med.sohag.edu.eg
01060386207
Yasser A Helmy, Professor
Contact

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Jul 2021. You cannot join it, but the record below documents what was studied.

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