An interventional study of Standard Program + Endurance and Strength training and Standard Program in Asthma, sponsored by Istituti Clinici Scientifici Maugeri SpA. Completed at 1 site in Italy. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2024-03-05.
Sponsored by Istituti Clinici Scientifici Maugeri SpA · Not applicable, Interventional, and Treatment
Emerging evidence suggests that regular exercise can complement medical treatment for asthma. Furthermore there are no specific recommendation on how plan exercise training. To the best of current knowledge, there isn't enough evidence of the effect of a strength training in subjects with asthma. Therefore the aim of this study is to evaluate the short and long term effects of a strength and endurance training compared with endurance training alone in subjects with asthma.
To the best of current knowledge, there isn't enough evidence of the effect of a strength training in subjects with asthma. Aim of the study is evaluate the short (after pulmonary rehabilitation) and long term (after 12 months) effects of a strength and endurance training compared with endurance training alone in improving quality of life and disease control in subjects with asthma of Global Initiative for Asthma (GINA) stage from 4 to 5.This is a prospective randomized control trial. Subjects with diagnosis of asthma according to the GINA guidelines admitted to a reference centre for inpatient pulmonary rehabilitation will be randomly assigned to study or control group.
3,921 studies on the registry are indexed under Asthma; 507 are open to participants now.
This study's enrollment of 58 is below the median of 83 across 2,752 interventional studies indexed under Asthma.
Browse Asthma studies →Istituti Clinici Scientifici Maugeri SpA is the lead sponsor of 113 studies on the registry; 46 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
twelve 30-minute daily sessions of supervised incremental exercise training over a period of 3 weeks.
Procedure: Standard Program + Endurance and Strength training · Procedure: Standard Program
twelve 30-minute daily sessions of supervised incremental exercise training over a period of 3 weeks twelve 30-minute daily sessions of supervised peripheral limb muscle training, 2 set of 6-12 repetitions
Procedure: Standard Program + Endurance and Strength training
Sessions of strength training added to a standard inpatient multidisciplinary programme
Standard inpatient multidisciplinary programme (including endurance training)
asthma related Quality of Life
Asthma Quality of Life Questionnaire (AQLQ). Range 0 (worst) - 7 (best)
Time frame: 4 weeks from enrollment
asthma related Quality of Life
Asthma Quality of Life Questionnaire (AQLQ). Range 0 (worst) - 7 (best)
Time frame: 1 year
Asthma control
Asthma Control Questionnaire (ACQ-6). Range 0 (best) - 6 (worst)
Time frame: 4 weeks from enrollment
Eosinophilic airway inflammation
Fractional Exhaled Nitric Oxide (FeNO),
Time frame: 4 weeks from enrollment
Aerobic capacity
Maximum oxygen capacity (VO2max) assessed by Cardio Pulmonary Exercise Test, (CPET).
Time frame: 4 weeks from enrollment
Quadriceps and biceps strength
Maximal Voluntary isometric Strength (MVS).
Time frame: 4 weeks from enrollment
Quadriceps and biceps strength
Maximal Voluntary isometric Strength (MVS).
Time frame: 1 year
Treatment satisfaction
Global Perceived Effect (GPE) score 1 (best) - 7 (worst)
Time frame: 1 year
Numbers of exacerbations
number of exacerbations in the last 12 months.
Time frame: 1 year
Asthma control
Asthma Control Questionnaire (ACQ-6) Range 0 (best) - 6 (worst)
Time frame: 1 year
Eosinophilic airway inflammation
Fractional Exhaled Nitric Oxide (FeNO).
Time frame: 1 year
Aerobic capacity
Maximum oxygen capacity(VO2max) assessed by Cardio Pulmonary Exercise Test (CPET)
Time frame: 1 year
This study is completed, as verified in Feb 2024. You cannot join it, but the record below documents what was studied.
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Istituti Clinici Scientifici Maugeri SpA