An interventional study of Beet root juice and Placebo juice in Type 2 Diabetes, sponsored by Karolinska Institutet. Recruiting at 1 site in Sweden. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-10-09.
Sponsored by Karolinska Institutet · Not applicable, Interventional, and Other
To investigate the effect of nitrate supplementation on red blood cell function in patients with type 2 diabetes.
10,925 studies on the registry are indexed under Diabetes Mellitus; 1,319 are open to participants now.
This study's planned enrollment of 20 is below the median of 80 across 8,367 interventional studies indexed under Diabetes Mellitus.
Browse Diabetes Mellitus studies →Karolinska Institutet is the lead sponsor of 1,113 studies on the registry; 267 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Type 2 diabetes
Exclusion Criteria:
Acute coronary syndrome Vegetarian diet Impaired renal function Absolute indication for proton pump inhibitor Ongoing treatment with organic nitrate Heart failure (ejection fraction \<35%) Any condition that interferes with the possibility to fulfill the study protocol
Nitrate-rich Beet root juice 70 ml bid
Dietary Supplement: Beet root juice
Nitrate-depleted beet root juice 70 ml bid
Dietary Supplement: Placebo juice
70 ml bid
70 ml bid
Percentage recovery of left ventricular function
Red blood cells are administered to an isolated rodent heart subjected to 25 min global ischemia and 60 min reperfusion. The percentage recovery during reperfusion is determined.
Time frame: 1 week
Plan to share: No
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Karolinska Institutet