An interventional study of abdominal fluid CA-125 levels test in Endometrial Carcinoma, sponsored by Erdemli State Hospital. Completed at 1 site in Turkey. Open to female participants aged 55 Years to 68 Years. Per ClinicalTrials.gov, last updated 2021-04-05.
Sponsored by Erdemli State Hospital · Not applicable, Interventional, and Diagnostic
In this prospective study, we aimed to investigate whether serum and abdominal washing fluid CA-125 levels correlated with postoperative histopathological parameters in patients with endometrial carcinoma.
Endometrial cancer was diagnosed with histopathological examination of the samples obtained by dilatation and curettage. Preoperative serum CA-125 levels were determined in all patients. Serum and abdominal washing fluid CA-125 levels were measured with a double antibody sandwich immunoenzymatic method, using Beckman Coulter DXI (Ireland) analyzer. In addition to routine preoperative investigations, MRI was done in patients who were thought to have an extension outside the uterus.
During surgery, abdominal exploration was performed first, and then an abdominal fluid sample was obtained for cytological examination and measurement of CA-125 level. One hundred milliliters of normal saline was used as the abdominal washing liquid to obtain the sample for CA-125 measurement. Subsequently, total abdominal hysterectomy and bilateral salpingo-oophorectomy (TAH + BSO) were performed.
6,745 studies on the registry are indexed under Carcinoma; 1,163 are open to participants now.
This study's enrollment of 50 is above the median of 45 across 5,174 interventional studies indexed under Carcinoma.
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Exclusion Criteria:
Women with endometrial carcinoma
Diagnostic Test: abdominal fluid CA-125 levels test
One hundred milliliters of normal saline was used as the abdominal washing liquid to obtain the sample for CA-125 measurement. Serum and abdominal washing fluid CA-125 levels were measured with a double antibody sandwich immunoenzymatic method, using Beckman Coulter DXI (Ireland) analyzer. I
Abdominal washing fluid CA-125 levels
Time frame: One year
Plan to share: No
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