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CompletedNCT04769193Updated Aug 11, 2026

A Clinical Trial Evaluating the Efficacy of a Skin Cream in Improving Facial Appearance and Skin Elasticity

An interventional study of Adipeau face cream in Atrophy, Hemifacial, Elastosis and Photoaging, sponsored by Adipeau Inc.. Completed at 1 site in United States. Open to participants aged 18 Years to 75 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-11.

Sponsored by Adipeau Inc. · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
35
Allocation
Not applicable
Ages
18 Years to 75 Years
Sex
All
01

Study summary

A Clinical Trial Evaluating Efficacy of a Skin Cream Targeting Dermal Fat in Improving the Skin Elasticity of Healthy Volunteers.

Read the detailed description

This is a single-arm study with subjects serving as their own controls. The study evaluates a face cream comprised of natural agents with adipogenic and lipolytic activities. The combination of adipogenic and lipolytic impulses is theorized to be more effective in promoting regeneration and healthy cell size in the dermal white adipose tissue than other approaches (e.g., adipogenic + lipogenic or anti-adipogenic + lipolytic). The health of the dermal white adipose tissue is reflected by the strength and elasticity of the skin and the distribution of volume in the face.

02

Conditions studied

  • Atrophy, Hemifacial
  • Elastosis
  • Photoaging

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Keywords

  • Sagging
  • Depletion
  • Atrophy
  • Photoaging
03

In context

Atrophy

828 studies on the registry are indexed under Atrophy; 122 are open to participants now.

This study's enrollment of 35 is close to the median of 34 across 603 interventional studies indexed under Atrophy.

Browse Atrophy studies →

Lead sponsor

This is the only study on the registry with Adipeau Inc. as lead sponsor.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

-

Exclusion criteria

Exclusion Criteria:

  • Plans to undergo facial skin resurfacing (e.g. laser, chemical peel, microneedling) during the study period
  • Plans to undergo injectable filler treatment.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
35 participants (actual)

Study arms

  • Experimental
    Adipeau face cream

    Cosmetic cream

    Other: Adipeau face cream

Interventions

  • OtherAdipeau face cream

    Adipeau face cream contains the natural actives Carthamus Tinctorius (Safflower) Seed Oil and Kaempferia Parviflora Rhizome Extract (Black Ginger).

06

What researchers measure

Primary outcomes

  1. Change in Skin Elasticity

    Elasticity measured by DermaLab Skin Elasticity Meter.

    Time frame: Six months and 12 months..

  2. Change in Skin Volume

    Increases and decreases measured by Cherry Imaging 3D Scanning System.

    Time frame: Six months and 12 Months.

Secondary outcomes

  1. FaceQ skin satisfaction surveys

    Satisfaction With Skin, Appraisal of Lower Eyelids, Satisfaction with Cheeks, Adverse Effects

    Time frame: Two, Six and 12 Months.

07

Study locations

1 site
  • Thomas Romo Plastic Surgery
    New York, New York 10021, United States
08

References and documents

Publications

  • Galanin I, Nicu C, Tower JI. Facial Fat Fitness: A New Paradigm to Understand Facial Aging and Aesthetics. Aesthetic Plast Surg. 2021 Feb;45(1):151-163. doi: 10.1007/s00266-020-01933-6. Epub 2020 Sep 10. PubMed 32914326 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 11, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT04769193
Lead sponsor
Adipeau Inc.
Collaborators
Romo Plastic Surgery
Responsible party
Sponsor
First posted
Feb 24, 2021
Start date
Jan 27, 2021
Primary completion
Apr 15, 2022
Completion
Apr 15, 2022
Last update
Aug 11, 2026

Study contacts

Jacob Tower, MD
principal investigator · Romo Plastic Surgery

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.

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