An interventional study of Magnetic Resonance Imaging in Bariatric Surgery, sponsored by Assistance Publique - Hôpitaux de Paris. Completed at 1 site in France. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-08-13.
Sponsored by Assistance Publique - Hôpitaux de Paris · Not applicable, Interventional, and Diagnostic
The investigators propose an exploratory study aiming at assessing the impact of surgical bariatric treatment on the improvement of pancreatic lesions detected by MRI.
Pancreatic MRI will be performed in severe-obese patients with a planned bariatric surgery, before and 6 months after bariatric surgery.
To assess the impact of bariatric surgery on pancreatic Magnetic Resonance Imaging (MRI) parameters in severe-obese patients
Assistance Publique - Hôpitaux de Paris is the lead sponsor of 3,505 studies on the registry; 1,006 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Secondary exclusion criteria :
Recruitment of patient with planned bariatric surgery in Louis Mourier Hospital by the nutritionist, during the preoperative day hospitalisation (performed during the multidisciplinary preparation for bariatric surgery) when patients are deemed eligible for bariatric surgery according to HAS (High Authority of Health) criteria. Programming of MRI in the month between preoperative visit and surgery. During this exam without injection of contrast agents in the radiology department of Louis Mourier Hospital, additional sequences with specific acquisitions as previously validated in humans will be performed for the study. Bariatric surgery will be performed as in usual care in Louis Mourier hospital. The same MRI will be performed in day hospitalization scheduled 6 months after surgery.
Radiation: Magnetic Resonance Imaging
Pancreatic MRI will be performed in severe-obese patients with a planned bariatric surgery, before and 6 months after bariatric surgery.
Quantitative MRI parameters
Pancreatic fat content
Time frame: 6 months after inclusion
Quantitative MRI parameters
diffusion parameters (mm² / s)
Time frame: 6 months after inclusion
Quantitative MRI parameters
transverse magnetization relaxation rate (Hz)
Time frame: 6 months after inclusion
Quantitative MRI parameters
longitudinal relaxation rate (Hz)
Time frame: 6 months after inclusion
Quantitative MRI parameters
visco-elastic parameters by measure of tissue stiffness (kPa)
Time frame: 6 months after inclusion
Metabolic and anthropometric parameters before and after bariatric surgery
BMI
Time frame: 6 months after inclusion
Metabolic and anthropometric parameters before and after bariatric surgery
% fat mass in impedance
Time frame: 6 months after inclusion
Metabolic and anthropometric parameters before and after bariatric surgery
weight loss in percent of preoperative body weight
Time frame: 6 months after inclusion
Metabolic and anthropometric parameters before and after bariatric surgery
excess weight loss
Time frame: 6 months after inclusion
Metabolic and anthropometric parameters before and after bariatric surgery
blood pressure
Time frame: 6 months after inclusion
Metabolic and anthropometric parameters before and after bariatric surgery
HOMA-IR index
Time frame: 6 months after inclusion
lipids parameters
total cholesterol, HDL, LDL, triglycerides
Time frame: 6 months after inclusion
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Assistance Publique - Hôpitaux de Paris