An interventional study of Early Supported discharge with home based Rehabilitation and Conventional rehabilitation in Stroke, sponsored by Seoul National University Bundang Hospital. Completed at 1 site in Korea, Republic of. Open to participants aged 20 Years and older. Per ClinicalTrials.gov, last updated 2025-06-19.
Sponsored by Seoul National University Bundang Hospital · Not applicable, Interventional, and Treatment
The study aims to examine the effect of early supported discharge (ESD) service on the functional outcomes and quality of life of acute stroke patients with mild to moderate disability in Korea.
The study is a double-armed prospective multi-centered, assessor-blinded randomized controlled trial comparing the effect of ESD program with conventional rehabilitation program.
Early Supported Discharge (ESD) is a form of medical service applicable to acute stroke patients with mild to moderate disabilities. ESD service was developed to facilitate patient to their daily livings at home, reduce the length of stay in the hospital with possibly better or equivalent outcomes for patients and caregivers.
ESD service has been proven to be non-inferior in the functional and quality of life measures as well as cost-effective, compared to the conventional rehabilitation service in many countries, however the effectiveness of ESD service may differ among countries and medical, economical circumstances. This study aims to examine the effect of ESD service on the acute stroke patients with mild to moderate disabilities in Korea and demonstrate its feasibility as an alternative medical service option to those patients.
7,286 studies on the registry are indexed under Stroke; 2,007 are open to participants now.
This study's enrollment of 67 is above the median of 50 across 5,369 interventional studies indexed under Stroke.
Browse Stroke studies →Seoul National University Bundang Hospital is the lead sponsor of 368 studies on the registry; 55 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Patients in the ESD group will be discharged to home as soon as the acute medical treatment is finished. The patients will follow a pre-planned ESD program which consists of home-based rehabilitation (at least 30 minutes of physical therapy and 30 minutes of occupational therapy per week) offered by therapists. The ESD team will also provide social/medical services as needed. The ESD program will be provided till 1 months after discharge point.
Other: Early Supported discharge with home based Rehabilitation
The patients in CR group will be provided with inpatient rehabilitation after the acute medical treatment is finished. The length of inpatient rehabilitation may depend on the hospital's current program. Patients will be provided with outpatient based rehabilitation program if needed after discharge.
Other: Conventional rehabilitation
Treatment by Physiotherapist and occupational therapist at least 30 minutes each, per week provided at home.
Treatment will be provided according to current hospital's stroke rehabilitation program.
changes in Korean modified Barthel Index (K-MBI)
K-MBI is an ordinal scale used to measure performance in activities of daily living(ADL). score ranges from 0 to 100, higher score meaning better ADL function.
Time frame: Baseline, 1 month after discharge, 3 months after onset, changes from baseline
modified Rankin Scale (mRS)
mRS is a scale used for measuring the degree of disability or dependence in the daily activities of people with stroke. Scale ranges from 0-6, with 0 meaning no symptoms and 6 meaning dead.
Time frame: Baseline, 1 month after discharge, 3 months after onset
Korean Instrumental Activities of Daily Living (K-IADL)
K-IADL assesses a person's ability to perform tasks such as using a telephone, doing laundry, and handling finances. The scale ranges from 0 to 100, higher score meaning better IADL function.
Time frame: 1 month after discharge, 3 months after onset
Korean Reintegration to Normal Life Index (K-RNLI)
K-RNLI assesses the degree of individuals who have experienced stroke achieve reintegration into normal social activities. The scale ranges from 0-100 with higher score meaning better reintegration to normal life.
Time frame: 1 month after discharge, 3 months after onset
Patient Health Questionnaire-9 (PHQ-9)
PHQ-9 is a instrument for screening, diagnosing and measuring the severity of depression. The scale ranges from 0-27 with higher score indicating severer depression.
Time frame: Baseline, 1 month after discharge, 3 months after onset
Korean Stroke Impact Scale ver 3.0 (K-SIS)
K-SIS evaluates disability and health-related quality of life after stroke. It consists of 8 domains each score ranges from 0-100 with higher score meaning better quality of life.
Time frame: 1 month after discharge, 3 months after onset
European Quality of Life-5 Dimensions-5 Levels (EQ-5D-5L)
EQ-5D-5L evaluates the quality of life. The scale ranges from -0.066 to 0.904, lower value means worse quality of life.
Time frame: Baseline, 1 month after discharge, 3 months after onset
Fall Experience
Number of patients who experience fall within the period.
Time frame: 1 month after discharge, 3 months after onset
Mortality rate
Number of patients who died within the period.
Time frame: 1 month after discharge, 2 month after discharge(if needed), 3 months after onset
Readmission rate
Number of patients who were readmitted to the hospital within the period.
Time frame: 1 month after discharge, 2 month after discharge(if needed), 3 months after onset
Length of hospital stay
Number of days admitted to hospital for stroke treatment and post-stroke rehabilitation.
Time frame: 3 months after onset
Korean Zarit Burden Interview-22 (K-ZBI 22)
K-ZBI 22 assesses caregiver perceptions of burden in health, personal, social or financial domains. The scale ranges from 0-88 with higher score indicating higher burden.
Time frame: 1 month after discharge, 3 months after onset
Direct costs related to rehabilitation
Direct costs includes expenses for medical and rehabilitation services. It consists for inpatient cost, outpatient cost, home based rehabilitation cost.
Time frame: 1 month after discharge, 2 month after discharge(if needed), 3 months after onset
Indirect costs related to rehabilitation
Indirect costs means expenses needed for treatment and rehabilitation of the patients other tahn medical and rehabilitation services. Indirect costs include transportation expense and caregiver expense and productivity loss
Time frame: 1 month after discharge, 2 month after discharge(if needed), 3 months after onset
Plan to share: Undecided
This study is completed, as verified in Nov 2023. You cannot join it, but the record below documents what was studied.
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Seoul National University Bundang Hospital