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CompletedNCT04719806Updated Feb 16, 2021

MR Textural Analysis in Low Grade Gliomas

An observational study in Glioma, sponsored by Centre Hospitalier Universitaire de Nice. Completed at 1 site in France. Open to participants aged 19 Years to 77 Years. Per ClinicalTrials.gov, last updated 2021-02-16.

Sponsored by Centre Hospitalier Universitaire de Nice · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
80
Ages
19 Years to 77 Years
Sex
All
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Study summary

WHO classification of low grade gliomas now relies on tumoral molecular patterns, especially on IDH mutation and 1p/19q co deletion status. Textural analysis on medical imaging is studied in several fields, and could provide help in patients with brain tumor due to possible complications of brain biopsy. The purpose of this study is to determine if specific textural signature on MR imaging could be found for low grade gliomas. The investigators included patients with LGG diagnosed at CHU of Nice abd whose first MRI was available on the PACS of the CHU. Textural data are extraxted by tumoral contouring and specific logiciel (LifeX) and histopathologic data are assessed for each patient. Then the investigators analyze it to dtermine if textural indices can predict molecar status.

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Conditions studied

  • Glioma

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In context

Glioma

1,397 studies on the registry are indexed under Glioma; 351 are open to participants now.

This study's enrollment of 80 is close to the median of 88 across 238 observational studies indexed under Glioma.

Browse Glioma studies →

Lead sponsor

Centre Hospitalier Universitaire de Nice is the lead sponsor of 709 studies on the registry; 176 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
19 Years to 77 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Lower grade gliomas diagnosed at CHU of Nice with pre operative MRI and molecular data available

Inclusion criteria

LGG diagnosed at CHU of Nice abd whose first MRI was available on the PACS of the CHU

Exclusion criteria

Exclusion Criteria:

-

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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
80 participants (actual)
Patient registry
No
Biospecimen retention
Samples with dna
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What researchers measure

Primary outcomes

  1. review of MRI images to find clues that can predict molecular status

    Time frame: 9 years

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Study locations

1 site
  • Nice University Hospital
    Nice, 06000, France
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 16, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04719806
Lead sponsor
Centre Hospitalier Universitaire de Nice
Responsible party
Sponsor
First posted
Jan 22, 2021
Start date
Jan 1, 2010
Primary completion
May 1, 2019
Completion
May 1, 2019
Last update
Feb 16, 2021

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2021. You cannot join it, but the record below documents what was studied.

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