An interventional study of Transcranial alternating current stimulation in Working Memory, sponsored by University of Minnesota. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-12-17.
Sponsored by University of Minnesota · Not applicable, Interventional, and Basic science
This project will assess the feasibility of traveling wave transcranial alternating current stimulation (tACS) to modify working memory performance and large-scale brain connectivity in surgical epilepsy patients.
University of Minnesota is the lead sponsor of 1,184 studies on the registry; 195 are open to participants now.
Of its 132 completed or terminated interventional studies of FDA-regulated products, 91 (69%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
1. diminished capacity to consent;
Participants will experience traveling wave transcranial alternating current stimulation over the fronto-parietal regions at 4 Hz (theta condition).
Device: Transcranial alternating current stimulation
Participants will experience traveling wave transcranial alternating current stimulation over the fronto-parietal regions at 23 Hz (beta condition).
Device: Transcranial alternating current stimulation
Traveling wave transcranial alternating current stimulation will be applied at 4 Hz and 23 Hz over frontal and parietal brain areas in a randomized counterbalanced order.
Electrophysiological outcomes
Changes in spectral power and coherence of the local field potentials during transcranial electric stimulation relative to no stimulation periods.
Time frame: Immediate effect during stimulation
Working memory outcomes
Changes in working memory performance as measured with the N-back task (quantified with d-prime) during stimulation.
Time frame: Immediate effect during stimulation
Plan to share: Yes — De-identified data will be shared following the IRB guidelines and Data Sharing Policy for the National Institute of Mental Health (NOT-MH-19-033).
No publications or documents are linked to this record.
This study is completed, as verified in Dec 2025. You cannot join it, but the record below documents what was studied.
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University of Minnesota