ClinicalTrials.gg
Status unknownNCT04675203Updated Mar 30, 2021

Molecular Mechanisms of Tooth Eruption

An observational study in Tooth Eruption, sponsored by University Hospital, Strasbourg, France. Status unknown at 1 site in France. Open to participants aged 12 Years and older. Per ClinicalTrials.gov, last updated 2021-03-30.

Sponsored by University Hospital, Strasbourg, France · Observational

The sponsor has not verified this record recently (last verified Mar 2021), so the status shown — last known as Not yet recruiting — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
50
Ages
12 Years and older
Sex
All
01

Study summary

The main objective is to study the expression of molecules involved in tooth morphogenesis and eruption in healthy patients, and then to compare them with the results in patients with abnormalities of eruption (results obtained via a collection of biological samples of rare diseases already authorized).

02

Conditions studied

  • Tooth Eruption

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03

In context

Exanthema

68 studies on the registry are indexed under Exanthema; 11 are open to participants now.

This study's planned enrollment of 50 is below the median of 71 across 18 observational studies indexed under Exanthema.

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Lead sponsor

University Hospital, Strasbourg, France is the lead sponsor of 999 studies on the registry; 358 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
12 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Primary care clinic (Hôpitaux Universitaires de Strasbourg, France)

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patient over 12 years old who has given his consent
  • Patient whose legal representatives have given their consent for the use of operating waste destined for incineration
  • Patient undergoing oral surgery at the University Hospitals of Strasbourg, at the origin of the production of surgical waste such as teeth and bone fragments
  • Patient affiliated to a social security system

Exclusion criteria

Exclusion Criteria:

  • Refusal to participate
  • Patient with chronic systemic pathology
  • Patient under long-term drug treatment
  • Patient presenting a rare pathology with oral manifestation
  • Patient with a history of chemotherapy or head and neck radiotherapy
  • Non-French speaking patient / inability to give informed information
  • Patient under guardianship, curatorship or legal protection
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
50 participants (estimated)
Patient registry
No
Biospecimen retention
Samples without dna

Groups and cohorts

  • Normal tooth eruption

    Procedure: Tooth extraction

Interventions

  • ProcedureTooth extraction

    Tooth extraction

06

What researchers measure

Primary outcomes

  1. Expression and localization of molecules involved in tooth eruption

    Tissues are collected at the time of surgery and transferred during the day to the laboratory for analysis

    Time frame: During surgery

07

Study locations

1 site
  • Les Hôpitaux Universitaires de Strasbourg
    Strasbourg, 67091, France
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 30, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT04675203
Responsible party
Sponsor
First posted
Dec 19, 2020
Start date
Mar 2021 (estimated)
Primary completion
Mar 2021 (estimated)
Completion
Jan 2023 (estimated)
Last update
Mar 30, 2021

Study contacts

Marion STRUB
Contact
marion.strub@chru-strasbourg.fr
+33 3 88 69 56

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Mar 2021. You cannot join it, but the record below documents what was studied.

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