An observational study in Child Development, sponsored by Chang Gung Memorial Hospital. Status unknown at 1 site in Taiwan. Open to participants aged 1 Year to 18 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2020-12-17.
Sponsored by Chang Gung Memorial Hospital · Observational
A study of the relation between genetic biomarkers and child development in Taiwan.
The interaction between gene and environment (G×E) can be a very complicated process that influences child development. As a pilot study of child development biomarkers, this study investigates genes related to child development.
Chang Gung Memorial Hospital is the lead sponsor of 1,064 studies on the registry; 234 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Healthy children, children with developmental delay and adults whose children had gene abnormality were recruited.
Inclusion Criteria of Healthy Child:
Exclusion Criteria of Healthy Child:
Inclusion Criteria of Child with developmental delay:
Exclusion Criteria of Child with developmental delay:
Inclusion Criteria of Adult:
Healthy child
Patients with developmental delay
Scores of cognitive function 1
Bayley Scales of Infant and Toddler Development (Scores from 0 to 140, higher scores mean a better outcome.)
Time frame: baseline
Scores of cognitive function (2 y/o to 6 y/o)
Wechsler Preschool and Primary Scale of Intelligence (Scores from 0 to 200, higher scores mean a better outcome.)
Time frame: baseline
Scores of cognitive function (6 y/o to 16 y/o)
Wechsler Intelligence Scale for Children (Scores from 0 to 200, higher scores mean a better outcome.)
Time frame: baseline
Scores of cognitive function 3
Test of Nonverbal Intelligence-Fourth Edition (Scores from 0 to 60, higher scores mean a better outcome.)
Time frame: baseline
Scores of cognitive psychological function
Cantab MOT, PAL, SWM, SOC tests
Time frame: baseline
Scores of language function
Peabody Picture Vocabulary Test-Revised (Scores from 0 to 124, higher scores mean a better outcome.)
Time frame: baseline
Scores of language function 2
Preschool Language Impaired Scale(PLS)/Language Impaired Scale(LS) (PLS: Scores from 0 to 65, higher scores mean a better outcome. LS: Scores from 0 to 73, higher scores mean a better outcome.)
Time frame: baseline
Scores of general development
Comprehensive Developmental Inventory for Infants and Toddlers (Higher scores mean a better outcome.)
Time frame: baseline
Scores of social behavior 1
Clancy Behavior Scale (Scores from 0 to 42, lower scores mean a better outcome.)
Time frame: baseline
Scores of social behavior 2
Swanson, Nolan, and Pelham, Version IV (Lower scores mean a better outcome.)
Time frame: baseline
Scores of motor ability 1
The Berry-Buktenica Developmental Test of Visual-Motor Integration (Scores from 0 to 81, Higher scores mean a better outcome.)
Time frame: baseline
Scores of motor ability 2
Measure of Grip and Grasp (Higher scores mean a better outcome.)
Time frame: baseline
Gene test (Mircoarray)
Microarray (Use Axiom Genome-Wide TWB 2.0 Array Plate (TWB 2.0) to analyze SNPs of disease-related biomarkers.)
Time frame: baseline
Gene test (WES1)
Whole-Exome Sequencing (Use Burrows-Wheeler Aligner (BWA) 85 to screen out the variant discovery and genotyping.)
Time frame: baseline
Gene test (WES2)
Whole-Exome Sequencing (Use Samtools86 to screen out the variant discovery and genotyping.)
Time frame: baseline
Gene test (WES3)
Whole-Exome Sequencing (Use Picard to screen out the variant discovery and genotyping.)
Time frame: baseline
Gene test (WES4)
Whole-Exome Sequencing (Use Genome Analysis Toolkit (GATK) to screen out the variant discovery and genotyping.)
Time frame: baseline
Scores of participation(2-5 y/o)
Assessment of Preschool Children's Participation (Scores from 0 to 45, higher scores mean a better outcome.)
Time frame: baseline
Scores of participation(>6 y/o)
Children Assessment of Participation and Enjoyment and Preferences for Activity of Children (Higher scores mean a better outcome.)
Time frame: baseline
Scores of activities
Functional Independence Measure for Children (Scores from 18 to 126, higher scores mean a better outcome.)
Time frame: baseline
Scores of quality of life
Pediatric Quality of Life Inventory TM (Scores from 0 to 102, higher scores mean a better outcome.)
Time frame: baseline
This study is status unknown, as verified in Nov 2020. You cannot join it, but the record below documents what was studied.
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Chang Gung Memorial Hospital