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CompletedNCT04635813Updated Nov 19, 2020

The Impact of COVID-19 Pandemic on Thyroid Surgery in Italy: Results From a Nation-wide Multicentric Study

An observational study in Thyroid Disease, sponsored by University of Cagliari. Completed at 1 site in Italy. Per ClinicalTrials.gov, last updated 2020-11-19.

Sponsored by University of Cagliari · Observational

Study type
Observational
Model
Case-control
Time perspective
Retrospective
Enrollment
3,800
Sex
All
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Study summary

Italy has been on the frontline of the COVID-19 pandemic, caused by the coronavirus SARS-CoV-2, the need to focus resources to deal with the pandemic led to a disruption of routine surgical care, as well as activity for oncologic and chronic disease. The aim of this study was to evaluate the impact of COVID-19 pandemic on surgical activity of the Italian Units of Endocrine Surgery belonging to the SIUEC (Italian Society of Endocrine Surgery), the most important national scientific society of endocrine surgery.The aim of this study was to evaluate the impact of COVID-19 pandemic on surgical activity of the Italian Units of Endocrine Surgery belonging to the SIUEC (Italian Society of Endocrine Surgery), the most important national scientific society of endocrine surgery.

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Conditions studied

  • Thyroid Disease
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In context

COVID-19

7,640 studies on the registry are indexed under COVID-19; 488 are open to participants now.

This study's enrollment of 3,800 is above the median of 260 across 3,135 observational studies indexed under COVID-19.

Browse COVID-19 studies →

Lead sponsor

University of Cagliari is the lead sponsor of 82 studies on the registry; 17 are open to participants now.

Of its 5 completed or terminated interventional studies of FDA-regulated products, 1 (20%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients with thyroid disease

Inclusion criteria

  • patients that had undergone thyroidectomy during COVID-19 pandemic (from the 9th March to the 31st August 2020), defined as case group, or during the same period of the previous year (from the 9th Match to the 31st August 2019), defined as control group.

Exclusion criteria

Exclusion Criteria:

  • incomplete data
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Study design

Observational model
Case-control
Time perspective
Retrospective
Enrollment
3,800 participants (actual)
Patient registry
No

Groups and cohorts

  • Group 1 - COVID group

    Patients that underwent surgery during COVID-19 pandemic

    Procedure: Thyroidectomy

  • Group 2 - control group

    Patients that underwent surgery during 2019

    Procedure: Thyroidectomy

Interventions

  • ProcedureThyroidectomy

    Thyroidectomy

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What researchers measure

Primary outcomes

  1. Quantify the overall reduction of surgical activity for thyroid disease

    Time frame: 1 year

Secondary outcomes

  1. Quantify if the number of thyroid cancers operated during COVID-19 pandemic was significant different from the number of patients operated during the same period of the previous year

    Time frame: 1 year

  2. Quantify the number of aggressive tumors operated during COVID-19 pandemic and the same period of the previous year

    Comparison between the number of patients operated during COVID-19 pandemic with aggressive thyroid carcinoma (with lymph node metastasis, and/or extrathyroidal extension, and/or multifocality) with patients with aggressive thyroid carcinoma operated during the same period of the previous year

    Time frame: 1 year

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Study locations

1 site
  • AOU Cagliari
    Cagliari, CA 09100, Italy
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 19, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04635813
Lead sponsor
University of Cagliari
Responsible party
Fabio Medas (Assistant Professor, University of Cagliari) — Principal investigator
First posted
Nov 19, 2020
Start date
Mar 10, 2020
Primary completion
Sep 30, 2020
Completion
Nov 12, 2020
Last update
Nov 19, 2020

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Nov 2020. You cannot join it, but the record below documents what was studied.

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